Endocrine disrupting chemicals (EDCs) and female cancer: Informing the patients - PubMed (original) (raw)

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Endocrine disrupting chemicals (EDCs) and female cancer: Informing the patients

Dominik Rachoń. Rev Endocr Metab Disord. 2015 Dec.

Abstract

Breast and uterine cancer are the most frequent female gender related neoplasms whose growth is mostly estrogen dependent. Therefore, any EDC exhibiting estrogenic effects may increase the risk of these two malignancies. This review focuses on the potential role of EDCs with estrogenic potential on the risk of breast and uterine neoplasms but also points to the possible role of the exposure to EDCs in the pathogenesis of ovarian and cervical cancer. It also underlines the necessity of informing the public about the presence of EDCs in common consumer products, their detrimental health effects and methods of reducing the exposure risk.

Keywords: Breast cancer; Cervical cancer; Endocrine disrupting chemicals (EDCs); Female cancer; Ovarian cancer; Uterine cancer.

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References

    1. Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, et al. Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev. 2009;30(4):293–342. doi: 10.1210/er.2009-0002. - DOI - PMC - PubMed
    1. Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, et al. Executive summary to EDC-2: the endocrine Society’s second scientific statement on endocrine-disrupting chemicals. Endocr Rev. 2015;36(6):593–602. doi: 10.1210/er.2015-1093. - DOI - PMC - PubMed
    1. Rachoń D, Vortherms T, Seidlovà-Wuttke D, Wuttke W. Dietary daidzein and puerarin do not affect pituitary LH expression but exert uterotropic effects in ovariectomized rats. Maturitas. 2007;57(2):161–170. doi: 10.1016/j.maturitas.2006.12.003. - DOI - PubMed
    1. Rachoń D, Vortherms T, Seidlovà-Wuttke D, Wuttke W. Effects of dietary equol on the pituitary of the ovariectomized rats. Horm Metab Res. 2007;39(4):256–61. doi:10.1055/s-2007-973074. - PubMed
    1. Diamanti-Kandarakis E, Palioura E, Kandarakis SA, Koutsilieris M. The impact of endocrine disruptors on endocrine targets. Horm Metab Res = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2010;42(8):543–552. doi: 10.1055/s-0030-1252034. - DOI - PubMed

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