Ia-positive dendritic cells form a tightly meshed network within the human airway epithelium - PubMed (original) (raw)

Ia-positive dendritic cells form a tightly meshed network within the human airway epithelium

P G Holt et al. Clin Exp Allergy. 1989 Nov.

Abstract

In this report we have employed an alternative tissue-sectioning procedure which provides a plan view of intra-epithelial cell populations within the airway wall. Immunoperoxidase staining of such sections for class II MHC (Ia) antigen revealed the presence of a highly developed intra-epithelial network of Ia-positive dendritic cells, which was not evident employing conventional cross- or longitudinal tissue sections. This finding has important implications for the study of mechanisms underlying allergic and infectious diseases of the respiratory tract.

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