Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast - PubMed (original) (raw)
Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast
R Strich et al. Proc Natl Acad Sci U S A. 1989 Dec.
Abstract
Mutations in Saccharomyces cerevisiae have been identified that derepress early meiotic genes functioning in separable pathways required for normal meiotic development. The phenotypes of these ume (unscheduled meiotic gene expression) mutations suggest that their wild-type alleles encode negative regulators acting downstream of both the cell-type and nutritional controls of meiosis. These newly defined loci do not affect either general transcription or transcription of meiotic genes expressed later in meiosis and spore formation.
Similar articles
- SSP1, a gene necessary for proper completion of meiotic divisions and spore formation in Saccharomyces cerevisiae.
Nag DK, Koonce MP, Axelrod J. Nag DK, et al. Mol Cell Biol. 1997 Dec;17(12):7029-39. doi: 10.1128/MCB.17.12.7029. Mol Cell Biol. 1997. PMID: 9372934 Free PMC article. - Mitochondrial activity is required for the expression of IME1, a regulator of meiosis in yeast.
Treinin M, Simchen G. Treinin M, et al. Curr Genet. 1993 Mar;23(3):223-7. doi: 10.1007/BF00351500. Curr Genet. 1993. PMID: 8435851 - UME6 is a key regulator of nitrogen repression and meiotic development.
Strich R, Surosky RT, Steber C, Dubois E, Messenguy F, Esposito RE. Strich R, et al. Genes Dev. 1994 Apr 1;8(7):796-810. doi: 10.1101/gad.8.7.796. Genes Dev. 1994. PMID: 7926768 - Control of meiotic gene expression in Saccharomyces cerevisiae.
Mitchell AP. Mitchell AP. Microbiol Rev. 1994 Mar;58(1):56-70. doi: 10.1128/mr.58.1.56-70.1994. Microbiol Rev. 1994. PMID: 8177171 Free PMC article. Review. - Dual regulation of meiosis in yeast.
Malone RE. Malone RE. Cell. 1990 May 4;61(3):375-8. doi: 10.1016/0092-8674(90)90517-i. Cell. 1990. PMID: 2185888 Review.
Cited by
- In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors.
Wang H, Stillman DJ. Wang H, et al. Proc Natl Acad Sci U S A. 1990 Dec;87(24):9761-5. doi: 10.1073/pnas.87.24.9761. Proc Natl Acad Sci U S A. 1990. PMID: 2263626 Free PMC article. - Analysis of RIM11, a yeast protein kinase that phosphorylates the meiotic activator IME1.
Bowdish KS, Yuan HE, Mitchell AP. Bowdish KS, et al. Mol Cell Biol. 1994 Dec;14(12):7909-19. doi: 10.1128/mcb.14.12.7909-7919.1994. Mol Cell Biol. 1994. PMID: 7969131 Free PMC article. - Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p).
Cooper KF, Mallory MJ, Smith JB, Strich R. Cooper KF, et al. EMBO J. 1997 Aug 1;16(15):4665-75. doi: 10.1093/emboj/16.15.4665. EMBO J. 1997. PMID: 9303311 Free PMC article. - The dual role of cyclin C connects stress regulated gene expression to mitochondrial dynamics.
Strich R, Cooper KF. Strich R, et al. Microb Cell. 2014 Sep 14;1(10):318-324. doi: 10.15698/mic2014.10.169. Microb Cell. 2014. PMID: 28357211 Free PMC article. Review. - The extent of cyclin C promoter occupancy directs changes in stress-dependent transcription.
Stieg DC, Cooper KF, Strich R. Stieg DC, et al. J Biol Chem. 2020 Nov 27;295(48):16280-16291. doi: 10.1074/jbc.RA120.015215. Epub 2020 Sep 15. J Biol Chem. 2020. PMID: 32934007 Free PMC article.
References
- Genetics. 1976 Feb;82(2):187-206 - PubMed
- Mol Cell Biol. 1989 May;9(5):2142-52 - PubMed
- Genetics. 1980 Nov;96(3):589-611 - PubMed
- J Mol Biol. 1981 Apr 15;147(3):357-72 - PubMed
- Proc Natl Acad Sci U S A. 1982 Mar;79(5):1578-82 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases