Linear chromosome of Borrelia burgdorferi - PubMed (original) (raw)
Review
. 1989 Oct;140(8):507-16.
doi: 10.1016/0923-2508(89)90083-1.
Affiliations
- PMID: 2696058
- DOI: 10.1016/0923-2508(89)90083-1
Free article
Review
Linear chromosome of Borrelia burgdorferi
C Baril et al. Res Microbiol. 1989 Oct.
Free article
Abstract
The DNA organization of several European and American isolates of Borrelia burgdorferi, the aetiological agent of Lyme disease, was analysed in pulse-field agarose gel electrophoresis. The results of in situ cell lysis in agarose plugs demonstrated a unique arrangement for the DNA of this spirochete. The chromosome of Borrelia behaved as a eukaryotic linear chromosome with a size of around 1,000 kb. The genome also comprised several circular and linear plasmids which varied in size from 15 to 60 kb.