Phytochemical and Biological Investigations of Conradina canescens - PubMed (original) (raw)
- PMID: 26996011
Phytochemical and Biological Investigations of Conradina canescens
Noura S Dosoky et al. Nat Prod Commun. 2016 Jan.
Abstract
Conradina canescens (Lamiaceae) is an endemic evergreen shrub native to Florida, Mississippi and Alabama, with no phytochemical or biological studies registered in the literature. Thus, a phytochemical study and a toxicity analysis of the chloroform extract obtained from the leaves of C. canescens were performed for the first time. In our preliminary screening, the crude extract and its fractions were subjected to cytotoxicity, antimicrobial and antileishmanial bioassays. The crude extract showed substantial cytotoxic, antimicrobial and antileishmanial activities. A total of six compounds, namely ursolic acid (62.4%), betulin (8.4%), β-amyrin (4.6%), myrtenic acid (2.9%), n-tetracosane (1.4%), and oleanolic acid (1.1%), were isolated. The structures of the isolated compounds were established by spectroscopic studies using NMR and IR spectroscopy.
Similar articles
- The Genus Conradina (Lamiaceae): A Review.
Dosoky NS, Setzer WN. Dosoky NS, et al. Plants (Basel). 2018 Mar 11;7(1):19. doi: 10.3390/plants7010019. Plants (Basel). 2018. PMID: 29534498 Free PMC article. Review. - Identification of antioxidant and antimicrobial compounds of Lippia species by bioautography.
Fabri RL, Nogueira MS, Moreira Jdos R, Bouzada ML, Scio E. Fabri RL, et al. J Med Food. 2011 Jul-Aug;14(7-8):840-6. doi: 10.1089/jmf.2010.0141. Epub 2011 Apr 10. J Med Food. 2011. PMID: 21476886 - New Adenosine Derivatives from Aizoon canariense L.: In Vitro Anticholinesterase, Antimicrobial, and Cytotoxic Evaluation of Its Extracts.
Bakr RO, El-Behairy MF, Elissawy AM, Elimam H, Fayed MAA. Bakr RO, et al. Molecules. 2021 Feb 24;26(5):1198. doi: 10.3390/molecules26051198. Molecules. 2021. PMID: 33668096 Free PMC article. - Anti-inflammatory, antioxidant and antifungal activity of Chuquiraga spinosa.
Casado R, Landa A, Calvo J, García-Mina JM, Marston A, Hostettmann K, Calvo MI. Casado R, et al. Pharm Biol. 2011 Jun;49(6):620-6. doi: 10.3109/13880209.2011.577436. Pharm Biol. 2011. PMID: 21554005 - Chemical and pharmacological progress on polyacetylenes isolated from the family apiaceae.
Chen Y, Peng S, Luo Q, Zhang J, Guo Q, Zhang Y, Chai X. Chen Y, et al. Chem Biodivers. 2015 Apr;12(4):474-502. doi: 10.1002/cbdv.201300396. Chem Biodivers. 2015. PMID: 25879495 Review.
Cited by
- Antimicrobial activity of spiculisporic acid isolated from endophytic fungus Aspergillus cejpii of Hedera helix against MRSA.
Osama S, El Sherei M, Al-Mahdy DA, Bishr M, Salama O, Raafat MM. Osama S, et al. Braz J Microbiol. 2024 Mar;55(1):515-527. doi: 10.1007/s42770-023-01224-7. Epub 2024 Jan 17. Braz J Microbiol. 2024. PMID: 38231376 Free PMC article. - Allelopathic Properties of Lamiaceae Species: Prospects and Challenges to Use in Agriculture.
Islam AKMM, Suttiyut T, Anwar MP, Juraimi AS, Kato-Noguchi H. Islam AKMM, et al. Plants (Basel). 2022 May 31;11(11):1478. doi: 10.3390/plants11111478. Plants (Basel). 2022. PMID: 35684250 Free PMC article. Review. - Biological Activities and Safety of Citrus spp. Essential Oils.
Dosoky NS, Setzer WN. Dosoky NS, et al. Int J Mol Sci. 2018 Jul 5;19(7):1966. doi: 10.3390/ijms19071966. Int J Mol Sci. 2018. PMID: 29976894 Free PMC article. Review. - The Genus Conradina (Lamiaceae): A Review.
Dosoky NS, Setzer WN. Dosoky NS, et al. Plants (Basel). 2018 Mar 11;7(1):19. doi: 10.3390/plants7010019. Plants (Basel). 2018. PMID: 29534498 Free PMC article. Review. - Free radical scavenging, α-glucosidase inhibitory and anti-inflammatory constituents from Indian sedges, Cyperus scariosus R.Br and Cyperus rotundus L.
Kakarla L, Katragadda SB, Tiwari AK, Kotamraju KS, Madhusudana K, Kumar DA, Botlagunta M. Kakarla L, et al. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S488-S496. doi: 10.4103/0973-1296.191467. Pharmacogn Mag. 2016. PMID: 27761080 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Medical