High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses - PubMed (original) (raw)
High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses
Daniela Huzly et al. Euro Surveill. 2016.
Free article
Abstract
The current Zika virus (ZIKV) epidemic in the Americas caused an increase in diagnostic requests in European countries. Here we demonstrate high specificity of the Euroimmun anti-ZIKV IgG and IgM ELISA tests using putative cross-reacting sera of European patients with antibodies against tick-borne encephalitis virus, dengue virus, yellow fever virus and hepatitis C virus. This test may aid in counselling European travellers returning from regions where ZIKV is endemic.
Keywords: ELISA; European travellers; Zika virus; cross-reactivity; flavivirus; specificity.
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