Preliminary characterization of the alcelaphine herpesvirus 1 genome - PubMed (original) (raw)
Comparative Study
. 1989 May:70 ( Pt 5):1141-50.
doi: 10.1099/0022-1317-70-5-1141.
Affiliations
- PMID: 2732713
- DOI: 10.1099/0022-1317-70-5-1141
Comparative Study
Preliminary characterization of the alcelaphine herpesvirus 1 genome
A Bridgen et al. J Gen Virol. 1989 May.
Abstract
Alcelaphine herpesvirus type 1 (AHV-1) is a causative agent of the fatal lymphoproliferative disease malignant catarrhal fever in deer and cattle. The genomes of the attenuated WC11 isolate and the virulent C500 isolate have been studied. The genome of WC11 comprises a region of unique DNA of approximately 130 kbp, which has a G + C content of 50%, and approximately 30 kbp of additional tandem direct repeat sequences with G + C content of 72%. WC11 possesses a major repeat sequence of 950 bp interspersed with a small number of related sequences of different length; these sequences are probably terminal in location. DNA from the C500 isolate has a similar restriction profile to that of WC11 in the unique region, but only one repeat sequence of 1050 bp is present. We propose, on the basis of biological and structural properties, that AHV-1 be included within the gamma 2 group of herpesviruses of which herpesvirus ateles is the prototype.
Similar articles
- The derivation of a restriction endonuclease map for Alcelaphine herpesvirus 1 DNA.
Bridgen A. Bridgen A. Arch Virol. 1991;117(3-4):183-92. doi: 10.1007/BF01310764. Arch Virol. 1991. PMID: 1850229 - Cloning and molecular characterization of the murine herpesvirus 68 genome.
Efstathiou S, Ho YM, Minson AC. Efstathiou S, et al. J Gen Virol. 1990 Jun;71 ( Pt 6):1355-64. doi: 10.1099/0022-1317-71-6-1355. J Gen Virol. 1990. PMID: 2351958 - Genome variation and evolution among herpes viruses.
Roizman B. Roizman B. Ann N Y Acad Sci. 1980;354:472-83. doi: 10.1111/j.1749-6632.1980.tb27986.x. Ann N Y Acad Sci. 1980. PMID: 6261658 Review. No abstract available. - Nonrandom clusters of palindromes in herpesvirus genomes.
Leung MY, Choi KP, Xia A, Chen LH. Leung MY, et al. J Comput Biol. 2005 Apr;12(3):331-54. doi: 10.1089/cmb.2005.12.331. J Comput Biol. 2005. PMID: 15857246 Free PMC article. Review.
Cited by
- Identification and characterisation of Gamma-herpesviruses in zoo artiodactyla.
Bianchessi L, Flach E, Monacchia G, Dagleish M, Maley M, Turin L, Rocchi MS. Bianchessi L, et al. Virol J. 2024 Feb 23;21(1):49. doi: 10.1186/s12985-024-02311-3. Virol J. 2024. PMID: 38395934 Free PMC article. - Wildebeest-Derived Malignant Catarrhal Fever: A Bovine Peripheral T Cell Lymphoma Caused by Cross-Species Transmission of Alcelaphine Gammaherpesvirus 1.
Gong M, Myster F, van Campe W, Roels S, Mostin L, van den Berg T, Vanderplasschen A, Dewals BG. Gong M, et al. Viruses. 2023 Feb 13;15(2):526. doi: 10.3390/v15020526. Viruses. 2023. PMID: 36851740 Free PMC article. Review. - Alcelaphine herpesvirus 1 genes A7 and A8 regulate viral spread and are essential for malignant catarrhal fever.
Myster F, Gong MJ, Javaux J, Suárez NM, Wilkie GS, Connelley T, Vanderplasschen A, Davison AJ, Dewals BG. Myster F, et al. PLoS Pathog. 2020 Mar 16;16(3):e1008405. doi: 10.1371/journal.ppat.1008405. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32176737 Free PMC article. - Genomic duplication and translocation of reactivation transactivator and bZIP-homolog genes is a conserved event in alcelaphine herpesvirus 1.
Myster F, van Beurden SJ, Sorel O, Suárez NM, Vanderplasschen A, Davison AJ, Dewals BG. Myster F, et al. Sci Rep. 2016 Dec 7;6:38607. doi: 10.1038/srep38607. Sci Rep. 2016. PMID: 27924936 Free PMC article.