Cross-sectional associations of objectively measured physical activity and sedentary time with sarcopenia and sarcopenic obesity in older men - PubMed (original) (raw)

Cross-sectional associations of objectively measured physical activity and sedentary time with sarcopenia and sarcopenic obesity in older men

Daniel A Aggio et al. Prev Med. 2016 Oct.

Abstract

This study investigated associations between objectively measured physical activity (PA) with sarcopenia and sarcopenic obesity in older British men. Participants were men aged 70-92years (n=1286) recruited from UK Primary Care Centres. Outcomes included (i) sarcopenia, defined as low muscle mass (lowest two fifths of the mid-upper arm muscle circumference distribution) accompanied by low muscular strength (hand grip strength <30kg) or low physical performance (gait speed≤0.8m/s); (ii) severe sarcopenia, required all three conditions; (iii) sarcopenic obesity defined as sarcopenia or severe sarcopenia and a waist circumference of >102cm. Independent variables included time spent in PA intensities measured by GT3x accelerometers, worn during one week in 2010-12. Multinomial regression models were used for cross-sectional analyses relating PA and sarcopenia. In total, 14.2% (n=183) of men had sarcopenia and a further 5.4% (n=70) had severe sarcopenia. 25.3% of sarcopenic or severely sarcopenic men were obese. Each extra 30min per day of moderate-to-vigorous PA (MVPA) was associated with a reduced risk of severe sarcopenia (relative risk [RR] 0.53, 95% confidence interval [CI] 0.30, 0.93) and sarcopenic obesity (RR 0.47 [95% CI 0.27, 0.84]). Light PA (LPA) and sedentary breaks were marginally associated with a reduced risk of sarcopenic obesity. Sedentary time was marginally associated with an increased risk of sarcopenic obesity independent of MVPA (RR 1.18 [95% CI 0.99, 1.40]). MVPA may reduce the risk of severe sarcopenia and sarcopenic obesity among older men. Reducing sedentary time and increasing LPA and sedentary breaks may also protect against sarcopenic obesity.

Keywords: Muscle mass; Physical activity; Sarcopenia; Sarcopenic obesity.

Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

PubMed Disclaimer

Figures

Fig. 1

Fig. 1

Recruitment flow chart – BRHS, 2010–12.

References

    1. Abe T., Mitsukawa N., Thiebaud R.S., Loenneke J.P., Loftin M., Ogawa M. Lower body site-specific sarcopenia and accelerometer-determined moderate and vigorous physical activity: the HIREGASAKI study. Aging Clin. Exp. Res. 2012;24(6):657–662. - PubMed
    1. Anon Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: executive summary. Expert panel on the identification, evaluation, and treatment of overweight in adults. Am. J. Clin. Nutr. 1998;68(4):899–917. - PubMed
    1. Atkins J.L., Whincup P.H., Morris R.W., Lennon L.T., Papacosta O., Wannamethee S.G. Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. J. Am. Geriatr. Soc. 2014;62(2):253–260. - PMC - PubMed
    1. Atkins J.L., Whincup P.H., Morris R.W., Wannamethee S.G. Low muscle mass in older men: the role of lifestyle, diet and cardiovascular risk factors. J. Nutr. Health Aging. 2014;18(1):26–33. - PubMed
    1. Bann D., Kuh D., Wills A.K., Adams J., Brage S., Cooper R. Physical activity across adulthood in relation to fat and lean body mass in early old age: findings from the medical research council national survey of health and development, 1946–2010. Am. J. Epidemiol. 2014;179(10):1197–1207. - PMC - PubMed

MeSH terms

Grants and funding

LinkOut - more resources