A general model for the transmembrane proteins of HIV and other retroviruses - PubMed (original) (raw)
A general model for the transmembrane proteins of HIV and other retroviruses
W R Gallaher et al. AIDS Res Hum Retroviruses. 1989 Aug.
Abstract
A hypothetical model of the transmembrane (TM) protein of human immunodeficiency virus (HIV) is proposed that is derived from the known structure of the influenza TM protein HA2. This model is consistent with computer algorithms of predicted protein structure and with known properties of TM proteins determined by sequence homology, site-directed mutations, peptide analogs, immunochemistry, or other biologic means. It is applicable to a wide variety of retroviral TM proteins differing widely in overall molecular weight.
Comment in
- Retroviral envelope glycoproteins contain a "leucine zipper"-like repeat.
Delwart EL, Mosialos G, Gilmore T. Delwart EL, et al. AIDS Res Hum Retroviruses. 1990 Jun;6(6):703-6. doi: 10.1089/aid.1990.6.703. AIDS Res Hum Retroviruses. 1990. PMID: 2364015 No abstract available.
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