Prevalence by Computed Tomographic Angiography of Coronary Plaques in South Asian and White Patients With Type 2 Diabetes Mellitus at Low and High Risk Using Four Cardiovascular Risk Scores (UKPDS, FRS, ASCVD, and JBS3) - PubMed (original) (raw)
. 2017 Mar 1;119(5):705-711.
doi: 10.1016/j.amjcard.2016.11.029. Epub 2016 Dec 2.
Aukelien C Dimitriu-Leen 1, Alexander R van Rosendael 2, Erik W van Zwet 3, Cornelis J Roos 4, Pranobe V Oemrawsingh 5, Aan V Kharagjitsingh 6, J Wouter Jukema 1, Victoria Delgado 1, Martin J Schalij 1, Jeroen J Bax 1, Arthur J H A Scholte 7
Affiliations
- PMID: 28024655
- DOI: 10.1016/j.amjcard.2016.11.029
Prevalence by Computed Tomographic Angiography of Coronary Plaques in South Asian and White Patients With Type 2 Diabetes Mellitus at Low and High Risk Using Four Cardiovascular Risk Scores (UKPDS, FRS, ASCVD, and JBS3)
Sanjay N Gobardhan et al. Am J Cardiol. 2017.
Abstract
The aim of this study was to explore the association between various cardiovascular (CV) risk scores and coronary atherosclerotic burden on coronary computed tomography angiography (CTA) in South Asians with type 2 diabetes mellitus and matched whites. Asymptomatic type 2 diabetic South Asians and whites were matched for age, gender, body mass index, hypertension, and hypercholesterolemia. Ten-year CV risk was estimated using different risk scores (United Kingdom Prospective Diabetes Study [UKPDS], Framingham Risk Score [FRS], AtheroSclerotic CardioVascular Disease [ASCVD], and Joint British Societies for the prevention of CVD [JBS3]) and categorized into low- and high-risk groups. The presence of coronary artery calcium (CAC) and obstructive coronary artery disease (CAD; ≥50% stenosis) was assessed using coronary CTA. Finally, the relation between coronary atherosclerosis on CTA and the low- and high-risk groups was compared. UKPDS, FRS, and ASCVD showed no differences in estimated CV risk between 159 South Asians and 159 matched whites. JBS3 showed a significant greater absolute CV risk in South Asians (18.4% vs 14.2%, p <0.01). Higher presence of CAC score >0 (69% vs 55%, p <0.05) and obstructive CAD (39% vs 27%, p <0.05) was observed in South Asians. South Asians categorized as high risk, using UKPDS, FRS, and ASCVD, showed more CAC and CAD compared than whites. JBS3 showed no differences. In conclusion, asymptomatic South Asians with type 2 diabetes mellitus more frequently showed CAC and obstructive CAD than matched whites in the population categorized as high-risk patients using UKPDS, FRS, and ASCVD as risk estimators. However, JBS3 seems to correlate best to CAC and CAD in both ethnicity groups compared with the other risk scores.
Copyright © 2016 Elsevier Inc. All rights reserved.
Similar articles
- Discordance between 10-year cardiovascular risk estimates using the ACC/AHA 2013 estimator and coronary artery calcium in individuals from 5 racial/ethnic groups: Comparing MASALA and MESA.
Al Rifai M, Cainzos-Achirica M, Kanaya AM, Kandula NR, Dardardi Z, Joshi PH, Patel J, Budoff M, Yeboah J, Guallar E, Blumenthal RS, Blaha MJ. Al Rifai M, et al. Atherosclerosis. 2018 Dec;279:122-129. doi: 10.1016/j.atherosclerosis.2018.09.015. Epub 2018 Sep 15. Atherosclerosis. 2018. PMID: 30262414 Free PMC article. - Use of imaging and clinical data to screen for cardiovascular disease in asymptomatic diabetics.
Rassi CH, Churchill TW, Tavares CA, Fahel MG, Rassi FP, Uchida AH, Wajchenberg BL, Lerario AC, Hulten E, Nasir K, Bittencourt MS, Rochitte CE, Blankstein R. Rassi CH, et al. Cardiovasc Diabetol. 2016 Feb 9;15:28. doi: 10.1186/s12933-016-0334-4. Cardiovasc Diabetol. 2016. PMID: 26861208 Free PMC article. - Subclinical atherosclerosis detected by coronary computed tomographic angiography in Qatar: a comparison between Qataris and south Asian migrants.
Schulman-Marcus J, Heo R, Gransar H, Suwaidi JA, Alkuwari M, Elmore K, Gomez MJ, Jayyousi A, Zirie M, Min JK, Peña JM. Schulman-Marcus J, et al. Int J Cardiovasc Imaging. 2017 Jun;33(6):927-935. doi: 10.1007/s10554-017-1073-7. Epub 2017 Jan 27. Int J Cardiovasc Imaging. 2017. PMID: 28130645 - Coronary artery calcification and ethnicity.
Shaikh K, Nakanishi R, Kim N, Budoff MJ. Shaikh K, et al. J Cardiovasc Comput Tomogr. 2019 Nov-Dec;13(6):353-359. doi: 10.1016/j.jcct.2018.10.002. Epub 2018 Oct 2. J Cardiovasc Comput Tomogr. 2019. PMID: 30322775 Review. - Predictive value of coronary computed tomography angiography in asymptomatic individuals with diabetes mellitus: Systematic review and meta-analysis.
Beller E, Meinel FG, Schoeppe F, Kunz WG, Thierfelder KM, Hausleiter J, Bamberg F, Schoepf UJ, Hoffmann VS. Beller E, et al. J Cardiovasc Comput Tomogr. 2018 Jul-Aug;12(4):320-328. doi: 10.1016/j.jcct.2018.04.002. Epub 2018 Apr 12. J Cardiovasc Comput Tomogr. 2018. PMID: 29685675 Review.
Cited by
- Association of diabetes with coronary artery calcium in South Asian adults and other race/ethnic groups: The multi-ethnic study of atherosclerosis and the mediators of atherosclerosis in South Asians living in America study.
Premyodhin N, Fan W, Arora M, Budoff MJ, Kanaya AM, Kandula N, Palaniappan L, Rana JS, Younus M, Wong ND. Premyodhin N, et al. Diab Vasc Dis Res. 2023 Sep-Oct;20(5):14791641231204368. doi: 10.1177/14791641231204368. Diab Vasc Dis Res. 2023. PMID: 37795703 Free PMC article. - Machine learning-based models to predict one-year mortality among Chinese older patients with coronary artery disease combined with impaired glucose tolerance or diabetes mellitus.
Li Y, Guan L, Ning C, Zhang P, Zhao Y, Liu Q, Ping P, Fu S. Li Y, et al. Cardiovasc Diabetol. 2023 Jun 14;22(1):139. doi: 10.1186/s12933-023-01854-z. Cardiovasc Diabetol. 2023. PMID: 37316853 Free PMC article. - Risk Factors Analysis and Management of Cardiometabolic-Based Chronic Disease in Low- and Middle-Income Countries.
Dutt C, Nunes Salles JE, Joshi S, Nair T, Chowdhury S, Mithal A, Mohan V, Kasliwal R, Sharma S, Tijssen J, Tandon N. Dutt C, et al. Diabetes Metab Syndr Obes. 2022 Feb 16;15:451-465. doi: 10.2147/DMSO.S333787. eCollection 2022. Diabetes Metab Syndr Obes. 2022. PMID: 35210795 Free PMC article. Review. - Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.
Zarkasi KA, Abdul Murad NA, Ahmad N, Jamal R, Abdullah N. Zarkasi KA, et al. Int J Environ Res Public Health. 2022 Jan 6;19(2):647. doi: 10.3390/ijerph19020647. Int J Environ Res Public Health. 2022. PMID: 35055468 Free PMC article. Review. - Carotid plaque imaging and the risk of atherosclerotic cardiovascular disease.
Zhu G, Hom J, Li Y, Jiang B, Rodriguez F, Fleischmann D, Saloner D, Porcu M, Zhang Y, Saba L, Wintermark M. Zhu G, et al. Cardiovasc Diagn Ther. 2020 Aug;10(4):1048-1067. doi: 10.21037/cdt.2020.03.10. Cardiovasc Diagn Ther. 2020. PMID: 32968660 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous