Improved cognition while cycling in Parkinson's disease patients and healthy adults - PubMed (original) (raw)

Improved cognition while cycling in Parkinson's disease patients and healthy adults

Audrey A Hazamy et al. Brain Cogn. 2017 Apr.

Abstract

Persons with Parkinson's disease (PD) are typically more susceptible than healthy adults to impaired performance when two tasks (dual task interference) are performed simultaneously. This limitation has by many experts been attributed to limitations in cognitive resources. Nearly all studies of dual task performance in PD employ walking or balance-based motor tasks, which are commonly impaired in PD. These tasks can be performed using a combination of one or two executive function tasks. The current study examined whether persons with PD would demonstrate greater dual task effects (DTEs) on cognition compared to healthy older adults (HOAs) during a concurrent cycling task. Participants with and without PD completed a battery of 12 cognitive tasks assessing visual and verbal processing in the following cognitive domains: speed of processing, controlled processing, working memory and executive function. Persons with PD exhibited impairments compared to healthy participants in select tasks (i.e., 0-back, 2-back and operation span). Further, both groups unexpectedly exhibited dual task facilitation of response times in visual tasks across cognitive domains, and improved verbal recall during an executive function task. Only one measure, 2-back, showed a speed-accuracy trade-off in the dual task. These results demonstrate that, when paired with a motor task in which they are not impaired, people with PD exhibit similar DTEs on cognitive tasks as HOAs, even when these task effects are facilitative. More generally, these findings demonstrate that pairing cognitive tasks with cycling may actually improve cognitive performance which may have therapeutic relevance to cognitive decline associated with aging and PD pathology.

Keywords: Cognition; Cognitive-motor interference; Dual task; Parkinson’s disease; Visual processing.

Copyright © 2017 Elsevier Inc. All rights reserved.

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Figures

Figure 1

Figure 1

Stimuli and Task Samples. Sample stimuli and task examples for 0-Back, 1-Back and 2-Back Tasks. a. 0-back reference stimuli. All other stimuli were compared to this reference. b. 1-Back task example. Participants compared the current stimulus on the screen to the stimulus one screen prior (both comparisons are No Match trials). c. 2-Back task example. Participants compared the current stimulus to the stimulus seen two screens prior.

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References

    1. Aarsland D, Andersen K, Larsen JP, Lolk A. Prevalence and Characteristics of Dementia in Parkinson Disease: An 8-Year Prospective Study. Archives of Neurology. 2003;60(3):387–392. - PubMed
    1. Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience. 1986;9(1):357–381. - PubMed
    1. Altmann LJP, Stegemöller E, Hazamy AA, Wilson JP, Okun MS, McFarland NR, … Hass CJ. Unexpected Dual Task Benefits on Cycling in Parkinson Disease and Healthy Adults: A Neuro-Behavioral Model. PLoS One. 2015:1–13. doi: 10.1371/journal.pone.0125470. - DOI - PMC - PubMed
    1. Al-Yahya E, Dawes H, Smith L, Dennis A, Howells K, Cockburn J. Cognitive motor interference while walking: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews. 2011;35(3):715–28. - PubMed
    1. Audiffren M. Acute exercise and psychological functions: A cognitive-energetic approach. In: McMorris T, Tomporowski P, Audiffren M, editors. Exercise and Cognitive Functions. Oxford, UK: Wiley-Blackwell; 2009. pp. 3–40.

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