Northern Shanghai Study: cardiovascular risk and its associated factors in the Chinese elderly-a study protocol of a prospective study design - PubMed (original) (raw)

Clinical Trial

. 2017 Mar 29;7(3):e013880.

doi: 10.1136/bmjopen-2016-013880.

Jing Xiong 1, Shikai Yu 1, Chen Chi 1, Ximin Fan 1, Bin Bai 1, Yiwu Zhou 1, Jiadela Teliewubai 1, Yuyan Lu 1, Henry Xu 1, Yi Zhang 1, Yawei Xu 1

Affiliations

Clinical Trial

Northern Shanghai Study: cardiovascular risk and its associated factors in the Chinese elderly-a study protocol of a prospective study design

Hongwei Ji et al. BMJ Open. 2017.

Abstract

Introduction: Cardiovascular (CV) diseases are the leading cause of death and disability in the world. Increasing lifespans and ageing populations also contribute to an increasing CV burden. However, in China, there were few well-designed cohort studies focusing on the elderly population, let alone an established CV risk score. The objective of this study is to establish a CV risk score based on a community-dwelling Chinese elderly population, determining the profile of the associated CV risk factors and target organ damages (TODs), so as to guide the later intervention.

Methods and analysis: The Northern Shanghai Study is an ongoing prospective community-based study. After enrolment, clinical examination, anthropometric measurement and a questionnaire will be administered to each participant at baseline and after every 2 years in the follow-up. Our tests and examinations include: blood/urine sample and biochemical measurements, office blood pressure recording, carotid ultrasonograph, echocardiograph, pulse wave velocity, pulse wave analysis, 4-limb blood pressure recording, body mass index, etc. Baseline measurement will also include the assessments on TODs and the conventional CV risk factors. In the follow-up, the incidence of CV events and mortality will be recorded. The Northern Shanghai Risk Score will be calculated, with considerations on CV risk factors and TODs.

Ethics and dissemination: This study was approved by the Shanghai Tenth People's Hospital Institutional Review Board. All participants signed a written consent form.

Trial registration number: NCT02368938; Pre-results.

Keywords: Chinese elderly; target organ damage.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

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Conflict of interest statement

Competing interests: None declared.

References

    1. Organization WH. Global Atlas on cardiovascular disease prevention and control. World Health Organization, 2011.
    1. Mozaffarian D, Benjamin EJ, Go AS et al. Heart disease and stroke statistics—2015 update: a report from the American Heart Association. Circulation 2015;131:e29–322. 10.1161/CIR.0000000000000152 - DOI - PubMed
    1. Organization WH. GLOBAL STATUS REPORT on noncommunicable diseases. World Health Organization, 2014.
    1. Yang G, Wang Y, Zeng Y et al. Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet 2013;381:1987–2015. 10.1016/S0140-6736(13)61097-1 - DOI - PMC - PubMed
    1. Xi B, Liu F, Hao Y et al. The growing burden of cardiovascular diseases in China. Int J Cardiol 2014;174:736–7. 10.1016/j.ijcard.2014.04.098 - DOI - PubMed

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