Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences - PubMed (original) (raw)

Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences

D E Ayer et al. Mol Cell Biol. 1988 May.

Abstract

Unlike most genes transcribed by RNA polymerase II, the simian virus 40 late transcription unit does not have a TATA box. To determine what sequences are required for initiation at the major late mRNA cap site of simian virus 40, clustered point mutations were constructed and tested for transcriptional activity in vitro and in vivo. Three promoter elements were defined. The first is centered 31 base pairs upstream of the cap site in a position normally reserved for a TATA box. The second is at the cap site. The third occupies a novel position centered 28 base pairs downstream of the cap site within a protein-coding sequence. The ability of RNA polymerase II to recognize this promoter suggests that there is greater variation in promoter architecture than had been believed previously.

PubMed Disclaimer

Similar articles

• Functional binding of the "TATA" box binding component of transcription factor TFIID to the -30 region of TATA-less promoters.
  Wiley SR, Kraus RJ, Mertz JE. Wiley SR, et al. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5814-8. doi: 10.1073/pnas.89.13.5814. Proc Natl Acad Sci U S A. 1992. PMID: 1321424 Free PMC article.
• Sequences locating the 5' ends of the major simian virus 40 late mRNA forms.
  Piatak M, Ghosh PK, Norkin LC, Weissman SM. Piatak M, et al. J Virol. 1983 Nov;48(2):503-20. doi: 10.1128/JVI.48.2.503-520.1983. J Virol. 1983. PMID: 6194314 Free PMC article.
• Characterization of a surrogate TATA box promoter that regulates in vitro transcription of the simian virus 40 major late gene.
  Nandi A, Das G, Salzman NP. Nandi A, et al. Mol Cell Biol. 1985 Mar;5(3):591-4. doi: 10.1128/mcb.5.3.591-594.1985. Mol Cell Biol. 1985. PMID: 2985959 Free PMC article.
• Simian virus 40 major late promoter: an upstream DNA sequence required for efficient in vitro transcription.
  Brady J, Radonovich M, Thoren M, Das G, Salzman NP. Brady J, et al. Mol Cell Biol. 1984 Jan;4(1):133-41. doi: 10.1128/mcb.4.1.133-141.1984. Mol Cell Biol. 1984. PMID: 6321950 Free PMC article.

Cited by

• Genetic analysis of the human papillomavirus type 31 differentiation-dependent late promoter.
  Bodily JM, Meyers C. Bodily JM, et al. J Virol. 2005 Mar;79(6):3309-21. doi: 10.1128/JVI.79.6.3309-3321.2005. J Virol. 2005. PMID: 15731225 Free PMC article.
• Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
  Hambraeus G, von Wachenfeldt C, Hederstedt L. Hambraeus G, et al. Mol Genet Genomics. 2003 Aug;269(5):706-14. doi: 10.1007/s00438-003-0883-6. Epub 2003 Jul 23. Mol Genet Genomics. 2003. PMID: 12884008
• Cell type-specific replication of simian virus 40 conferred by hormone response elements in the late promoter.
  Farrell ML, Mertz JE. Farrell ML, et al. J Virol. 2002 Jul;76(13):6762-70. doi: 10.1128/jvi.76.13.6762-6770.2002. J Virol. 2002. PMID: 12050389 Free PMC article.
• Different processing of an mRNA species in Bacillus subtilis and Escherichia coli.
  Persson M, Glatz E, Rutberg B. Persson M, et al. J Bacteriol. 2000 Feb;182(3):689-95. doi: 10.1128/JB.182.3.689-695.2000. J Bacteriol. 2000. PMID: 10633102 Free PMC article.

References

1. 1. J Mol Biol. 1982 Apr 5;156(2):229-43 - PubMed
2. 1. Nucleic Acids Res. 1981 Aug 25;9(16):3941-58 - PubMed
3. 1. Science. 1986 Oct 3;234(4772):53-9 - PubMed
4. 1. Cell. 1986 Sep 26;46(7):973-82 - PubMed
5. 1. J Mol Biol. 1981 Dec 15;153(3):589-618 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Europe PubMed Central
  • PubMed Central
  • Taylor & Francis

• Miscellaneous

  • NCI CPTAC Assay Portal