Mitochondrial DNA polymorphism among five Asian populations - PubMed (original) (raw)

Mitochondrial DNA polymorphism among five Asian populations

S Harihara et al. Am J Hum Genet. 1988 Aug.

Abstract

Mitochondrial DNA (mtDNA) polymorphisms were detected using 13 restriction enzymes on the total DNA obtained from blood samples of five Asian populations: Japanese and Ainu of northern Japan, Korean, Negrito (Aeta) of the Philippines, and Vedda of Sri Lanka. Of a total of 28 restriction-enzyme morphs detected, eight had not been reported previously. By combining the morphs, we were able to classify mtDNAs of 243 individuals into 20 mtDNA types. Phylogenetic analyses using maximum parsimony and genetic distance methods both showed that the Japanese, Ainu, and Korean populations were closely related to each other. Aeta was found to show a relatively close relationship to these three populations, confirming the conclusion from previous studies of blood markers. In contrast, Vedda was quite different from the other four populations.

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References

    1. Hum Biol Oceania. 1972 Aug;1(4):278-88 - PubMed
    1. Acta Genet Stat Med. 1964;14:41-51 - PubMed
    1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
    1. Cell. 1976 Oct;9(2):269-87 - PubMed
    1. J Mol Biol. 1977 Jun 15;113(1):237-51 - PubMed

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