VIRULENCE - PubMed (original) (raw)
VIRULENCE
J J Bull. Evolution. 1994 Oct.
Abstract
Why do parasites harm their hosts? Intuition suggests that parasites should evolve to be benign whenever the host is needed for transmission. Yet a growing theoretical literature offers several models to explain why natural selection may favor virulent parasites over avirulent ones. This perspective first organizes these models into a simple framework and then evaluates the empirical evidence for and against the models. There is relatively scant evidence to support any of the models rigorously, and indeed, there are only a few unequivocal observations of virulence actually evolving in parasite populations. These shortcomings are surmountable, however, and empirical models of host-parasite interactions have been developed for many kinds of pathogens so that the relevant data could be acquired in the near future.
Keywords: Evolution; microparasite; population biology; virulence; virus.
© 1994 The Society for the Study of Evolution.
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