Diabetes Mellitus and Heart Failure - PubMed (original) (raw)

Review

. 2017 Jul 1;120(1S):S37-S47.

doi: 10.1016/j.amjcard.2017.05.014. Epub 2017 May 30.

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Free article

Review

Diabetes Mellitus and Heart Failure

Michael Lehrke et al. Am J Cardiol. 2017.

Free article

Abstract

Epidemiologic and clinical data from the last 2 decades have shown that the prevalence of heart failure in diabetes is very high, and the prognosis for patients with heart failure is worse in those with diabetes than in those without diabetes. Experimental data suggest that various mechanisms contribute to the impairment in systolic and diastolic function in patients with diabetes, and there is an increased recognition that these patients develop heart failure independent of the presence of coronary artery disease or its associated risk factors. In addition, current clinical data demonstrated that treatment with the sodium glucose cotransporter 2 inhibitor empagliflozin reduced hospitalization for heart failure in patients with type 2 diabetes mellitus and high cardiovascular risk. This review article summarizes recent data on the prevalence, prognosis, pathophysiology, and therapeutic strategies to treat patients with diabetes and heart failure.

Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

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