Discovery of a Highly Divergent Coronavirus in the Asian House Shrew from China Illuminates the Origin of the Alphacoronaviruses - PubMed (original) (raw)

Maximum-likelihood phylogenetic trees of the amino acid sequences of the putative RdRp protein. (A) WESV and other coronaviruses. (B) WESV and other alphacoronaviruses. (C) WESV only. The asterisks indicate well-supported nodes (>70% bootstrap support). The scale bars indicate the numbers of amino acid substitutions per site. The virus genomes used in this study and their GenBank accession numbers are as follows: AlpacaCoV, alpaca respiratory coronavirus isolate CA08-1/2008 (

JQ410000

); BatCoV CDPHE15, bat coronavirus CDPHE15/USA/2006 (

KF430219

); BatCoV FJ2012, BtMf-AlphaCoV/FJ2012 (

KJ473799

); BatCoV YN2012, BtRf-AlphaCoV/YN2012 (

KJ473808

); BatCoV HuB2013, BtRf-AlphaCoV/HuB2013 (

KJ473807

); CamelCoV, camel alphacoronavirus isolate camel/Riyadh/Ry141/2015 (

KT368907

); CCoV K378, canine coronavirus strain K378 (

KC175340

); FCoV C1Je, feline coronavirus strain FCoV C1Je (

DQ848678

); BatCoV HKU2, bat coronavirus HKU2 strain HKU2/GD/430/2006 (

EF203064

); BatCoV HKU8, bat coronavirus HKU8 strain AFCD77 (

EU420139

); HCoV-229E, human coronavirus 229E (

AF304460

); HCoV-NL63, human coronavirus NL63 (

AY567487

); BatCoV JTAC2, bat coronavirus JTAC2 (

KU182966

); LRNV, Lucheng Rn rat coronavirus isolate Lucheng-19 (

KF294380

); BatCoV 1A, bat coronavirus 1A strain AFCD62 (

EU420138

); MCoV, mink coronavirus strain WD1127 (

HM245925

); PEDV, porcine epidemic diarrhea virus isolate ZJU/G1/2013 (

KU664503

); BatCoV HKU10, Rousettus bat coronavirus HKU10 isolate 183A (

JQ989270

); BatCoV SAX2011, BtMr-AlphaCoV/SAX2011 (

KJ473806

); BtCoV/512/2005, Scotophilus bat coronavirus 512 (

DQ648858

); TGEV, transmissible gastroenteritis virus virulent Purdue (

DQ811789

); BatCoV Zhejiang2013, bat Hp-betacoronavirus/Zhejiang2013 (

KF636752

); MERS-CoV, human betacoronavirus 2c EMC/2012 (

JX869059

); HCoV-HKU1, human coronavirus HKU1 (

AY597011

); BatCoV HKU9, bat coronavirus HKU9 (

EF065513

); SARS-CoV, SARS coronavirus WH20 (

AY772062

); BuCoV HKU11, bulbul coronavirus HKU11-934 (

FJ376619

); PorCoV HKU15, porcine coronavirus HKU15 strain HKU15-44 (

JQ065042

); MRCoV HKU18, magpie-robin coronavirus HKU18 strain HKU18-chu3 (

JQ065046

); WiCoV HKU20, wigeon coronavirus HKU20 strain HKU20-9243 (

JQ065048

); AIBV-Beaudette, avian infectious bronchitis virus Beaudette (

NC_001451

); DKCoV, duck coronavirus isolate DK/CH/HN/ZZ2004 (

JF705860

); BWCoV SW1, beluga whale coronavirus SW1 (

EU111742

); TCoV, turkey coronavirus isolate TCoV-ATCC (

EU022526

).