Congenital cytomegalovirus - who, when, what-with and why to treat? - PubMed (original) (raw)
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Congenital cytomegalovirus - who, when, what-with and why to treat?
Yinru Lim et al. J Infect. 2017 Jun.
Abstract
Congenital cytomegalovirus (CMV) is the commonest cause of congenital infection worldwide and the leading non-genetic cause of sensorineural hearing loss in children. Appropriate investigations and timely decision on treatment is required as studies have shown that treatment with antiviral therapy leads to improved hearing and neurodevelopmental outcomes in the long term when started in the first month of life. This paper outlines the epidemiology, investigations in the diagnosis of congenital CMV infection and current evidence surrounding treatment.
Keywords: Antiviral; Congenital; Cytomegalovirus; Ganciclovir; Infection; Valganciclovir.
© 2017 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
Comment in
- Prenatal valacyclovir treatment of fetal citomegalovirus infection: A case series.
De Santis M, De Luca C, Apicella M, D'Oria L, Lanzone A, Sanguinetti M, Valentini P, Scambia G, Masini L, Santangelo R. De Santis M, et al. J Infect. 2019 Nov;79(5):462-470. doi: 10.1016/j.jinf.2019.08.015. Epub 2019 Aug 26. J Infect. 2019. PMID: 31465779 No abstract available.
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