Intravenous magnesium in acute myocardial infarction - PubMed (original) (raw)

Clinical Trial

Intravenous magnesium in acute myocardial infarction

H S Rasmussen et al. Lancet. 1986.

Abstract

In a double-blind, placebo-controlled study, 273 patients with suspected acute myocardial infarction (AMI) were randomised to receive either magnesium intravenously or placebo immediately on admission to hospital. Of 130 patients with proven AMI 56 received magnesium and 74 received placebo. During the first 4 weeks after treatment mortality was 7% in the magnesium group and 19% in the placebo group. In the magnesium group 21% of patients had arrhythmias that needed treatment, compared with 47% in the placebo group. No adverse effects of intravenous magnesium were observed.

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• Deficiencies of Magnesium Replacement in the Critically Ill.
  Hammond DA, Stojakovic J, Kathe N, Tran J, Clem OA, Erbach K, King J. Hammond DA, et al. J Intensive Care Med. 2018 May;33(5):327. doi: 10.1177/0885066617735785. J Intensive Care Med. 2018. PMID: 29618293 No abstract available.

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