The c-erb-A protein is a high-affinity receptor for thyroid hormone - PubMed (original) (raw)

. 1986 Dec;324(6098):635-40.

doi: 10.1038/324635a0.

• PMID: 2879242
• DOI: 10.1038/324635a0

The c-erb-A protein is a high-affinity receptor for thyroid hormone

J Sap et al. Nature. 1986 Dec.

Abstract

Hormone binding and localization of the c-erb-A protein suggest that it is a receptor for thyroid hormone, a nuclear protein that binds to DNA and activates transcription. In contrast, the product of the viral oncogene v-erb-A is defective in binding the hormone but is still located in the nucleus.

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