[Effect of Quyu Huatan decoction on lipid metabolism and hormone levels of patients with polycystic ovary syndrome] - PubMed (original) (raw)
Randomized Controlled Trial
. 2016 Feb;41(3):532-535.
doi: 10.4268/cjcmm20160329.
[Article in Chinese]
Affiliations
- PMID: 28868876
- DOI: 10.4268/cjcmm20160329
Randomized Controlled Trial
[Effect of Quyu Huatan decoction on lipid metabolism and hormone levels of patients with polycystic ovary syndrome]
[Article in Chinese]
Wei-Jie Chen et al. Zhongguo Zhong Yao Za Zhi. 2016 Feb.
Abstract
To study the effect of prescription for removing blood stasis and resolving phlegm on lipid metabolism and hormone levels of patients with polycystic ovary syndrome. Totally 93 cases of patients with polycystic ovary syndrome treated in our hospital from March 2013 to July 2014 were randomly divided into control group and observation group. The observation group was treated by oral administration of Quyu Huatan decoction, while the control group was treated with metformin. The result indicated that the total effective rate of the observation group was significantly higher than that of the control group(χ²=632, P<0.05). After treatment, the score of syndrome for traditional Chinese medicine in the observation group was significantly lower than the control group(t=13.865,P<0.05). After treatment, the levels of TG, BMI, TC in the observation group were significantly lower than the control group(P<0.05), and the difference of HDL between the two groups were not significantly. After treatment, the levels of FSH, LH and T in the observation group were significantly lower than those in the control group(P<0.05). After treatment, FBG and INS in the two groups were significantly decreased(P<0.05); the FBG in the observation group was significantly lower than that in the control group(t=3.981, P<0.05), and the INS level in the observation group was significantly higher than that in the control group(t=6.472, P<0.05). In this study, we can find that the Quyu huatan decoction for removing blood stasis and resolving phlegm has a better clinical efficacy in the treatment of polycystic ovary syndrome. It not only ameliorates the secretion of variety sex hormone, but also regulates the body's metabolism of glucose and lipid, so it is worth clinical promotion and application.
Keywords: Quyu Huatan decoction; lipid metabolism; polycystic ovary syndrome; sex hormone.
Copyright© by the Chinese Pharmaceutical Association.
Conflict of interest statement
The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
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