Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations - PubMed (original) (raw)
Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations
M S Jacobson. Lancet. 1987.
Abstract
Two populations of immigrants to London and to the West Indies from the Indian subcontinent have higher than expected morbidity and mortality from atherosclerosis but do not show the commonly accepted major risk factors. This study investigated the hypothesis that ghee, a clarified butter product prized in Indian cooking, contains cholesterol oxides and could therefore be an important source of dietary exposure to cholesterol oxides and an explanation for the high atherosclerosis risk. Substantial amounts of cholesterol oxides were found in ghee (12.3% of sterols), but not in fresh butter, by thin-layer and high-performance-liquid chromatography. Dietary exposure to cholesterol oxides from ghee may offer a logical explanation for the high frequency of atherosclerotic complications in these Indian populations.
Similar articles
- Lipids and lipid oxidation with emphasis on cholesterol oxides in some Indian sweets available in London.
Ubhayasekera SJ, Kochhar SP, Dutta PC. Ubhayasekera SJ, et al. Int J Food Sci Nutr. 2006 Nov-Dec;57(7-8):451-8. doi: 10.1080/09637480600888834. Int J Food Sci Nutr. 2006. PMID: 17162324 - Cholesterol, ghee, and atherosclerosis.
Peterson D. Peterson D. Lancet. 1987 Oct 24;2(8565):970. doi: 10.1016/s0140-6736(87)91451-6. Lancet. 1987. PMID: 2889887 No abstract available. - Cholesterol in Indian ghee.
Nath BS, Murthy MK. Nath BS, et al. Lancet. 1988 Jul 2;2(8601):39. doi: 10.1016/s0140-6736(88)92962-5. Lancet. 1988. PMID: 2898634 No abstract available. - Dietary fat and experimental atherosclerosis.
Kritchevsky D. Kritchevsky D. Int J Tissue React. 1991;13(2):59-65. Int J Tissue React. 1991. PMID: 1955294 Review. - Atherogenicity of peanut oil in the rabbit.
[No authors listed] [No authors listed] Nutr Rev. 1972 Mar;30(3):70-2. doi: 10.1111/j.1753-4887.1972.tb05130.x. Nutr Rev. 1972. PMID: 4628342 Review. No abstract available.
Cited by
- Risk factors for non-fatal myocardial infarction in young South Asian adults.
Ismail J, Jafar TH, Jafary FH, White F, Faruqui AM, Chaturvedi N. Ismail J, et al. Heart. 2004 Mar;90(3):259-63. doi: 10.1136/hrt.2003.013631. Heart. 2004. PMID: 14966040 Free PMC article. - Plasma oxysterols and tocopherol in patients with diabetes mellitus and hyperlipidemia.
Murakami H, Tamasawa N, Matsui J, Yasujima M, Suda T. Murakami H, et al. Lipids. 2000 Mar;35(3):333-8. doi: 10.1007/s11745-000-0530-1. Lipids. 2000. PMID: 10783011 - Dietary factors in atherogenesis.
Wilson MM, Thomas DR. Wilson MM, et al. Curr Atheroscler Rep. 2003 Jul;5(4):324-30. doi: 10.1007/s11883-003-0056-4. Curr Atheroscler Rep. 2003. PMID: 12793974 Review. - Omega-3 fatty acids: their beneficial role in cardiovascular health.
Schwalfenberg G. Schwalfenberg G. Can Fam Physician. 2006 Jun;52(6):734-40. Can Fam Physician. 2006. PMID: 16812965 Free PMC article. Review. - Chemomodulation of carcinogen metabolising enzymes, antioxidant profiles and skin and forestomach papillomagenesis by Spirulina platensis.
Dasgupta T, Banejee S, Yadav PK, Rao AR. Dasgupta T, et al. Mol Cell Biochem. 2001 Oct;226(1-2):27-38. Mol Cell Biochem. 2001. PMID: 11768236
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical