Aspirin and Nonsteroidal Antiinflammatory Drugs Hypersensitivity and Management - PubMed (original) (raw)
Review
. 2017 Nov;37(4):727-749.
doi: 10.1016/j.iac.2017.07.008. Epub 2017 Sep 1.
Affiliations
- PMID: 28965637
- DOI: 10.1016/j.iac.2017.07.008
Review
Aspirin and Nonsteroidal Antiinflammatory Drugs Hypersensitivity and Management
Brian Modena et al. Immunol Allergy Clin North Am. 2017 Nov.
Abstract
Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) are widely used in the United States and throughout the world for a variety of indications. Several unique hypersensitivity syndromes exist to this class of medications, making them one of the common reasons for consultation to the allergist. The lack of any laboratory-based diagnostic studies to assist in identifying the culprits in these reactions make evaluation of aspirin and NSAID hypersensitivity challenging. Identifying patients appropriate for oral challenge and/or desensitization protocols is the standard pragmatic approach to this issue when it arises.
Keywords: Aspirin; Aspirin-exacerbated respiratory disease; Chronic spontaneous urticaria; Desensitization; Nonsteroidal antiinflammatory drugs; Oral challenge.
Copyright © 2017 Elsevier Inc. All rights reserved.
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