Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat - PubMed (original) (raw)
Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat
J R Bain et al. Plast Reconstr Surg. 1989 Jan.
Abstract
Quantification of peripheral nerve regeneration in animal studies of nerve injury and repair by histologic, morphologic, and electrophysiologic parameters has been controversial because such studies may not necessarily correlate with actual nerve function. This study modifies the previously described sciatic functional index (SFI), tibial functional index (TFI), and peroneal functional index (PFI) based on multiple linear regression analysis of factors derived from measurements of walking tracks in rats with defined nerve injuries. The factors that contributed to these formulas were print-length factor (PLF), toe-spread factor (TSF), and intermediary toe-spread factor (ITF). It was shown that animals with selective nerve injuries gave walking tracks that were consistent, predictable, and based on known neuromuscular deficits. The new formula for sciatic functional index was compared with previously described indices. The sciatic functional index, tibial functional index, and peroneal functional index offer the peripheral nerve investigator a noninvasive quantitative assessment of hindlimb motor function in the rat with selective hindlimb nerve injury.
Comment in
- Peroneal functional index.
Tetik C. Tetik C. Plast Reconstr Surg. 1997 Oct;100(5):1362. doi: 10.1097/00006534-199710000-00056. Plast Reconstr Surg. 1997. PMID: 9326810 No abstract available.
Similar articles
- Functional indices for sciatic, peroneal, and posterior tibial nerve lesions in the mouse.
Inserra MM, Bloch DA, Terris DJ. Inserra MM, et al. Microsurgery. 1998;18(2):119-24. doi: 10.1002/(sici)1098-2752(1998)18:2<119::aid-micr10>3.0.co;2-0. Microsurgery. 1998. PMID: 9674927 - Two-dimensional digital video ankle motion analysis for assessment of function in the rat sciatic nerve model.
de Ruiter GC, Spinner RJ, Alaid AO, Koch AJ, Wang H, Malessy MJ, Currier BL, Yaszemski MJ, Kaufman KR, Windebank AJ. de Ruiter GC, et al. J Peripher Nerv Syst. 2007 Sep;12(3):216-22. doi: 10.1111/j.1529-8027.2007.00142.x. J Peripher Nerv Syst. 2007. PMID: 17868249 - Methods for the experimental functional assessment of rat sciatic nerve regeneration.
Varejão AS, Melo-Pinto P, Meek MF, Filipe VM, Bulas-Cruz J. Varejão AS, et al. Neurol Res. 2004 Mar;26(2):186-94. doi: 10.1179/016164104225013833. Neurol Res. 2004. PMID: 15072638 Review.
Cited by
- Cholecalciferol (vitamin D₃) improves myelination and recovery after nerve injury.
Chabas JF, Stephan D, Marqueste T, Garcia S, Lavaut MN, Nguyen C, Legre R, Khrestchatisky M, Decherchi P, Feron F. Chabas JF, et al. PLoS One. 2013 May 31;8(5):e65034. doi: 10.1371/journal.pone.0065034. Print 2013. PLoS One. 2013. PMID: 23741446 Free PMC article. - Functional Gait Assessment Using Manual, Semi-Automated and Deep Learning Approaches Following Standardized Models of Peripheral Nerve Injury in Mice.
Umansky D, Hagen KM, Chu TH, Pathiyil RK, Alzahrani S, Ousman SS, Midha R. Umansky D, et al. Biomolecules. 2022 Sep 23;12(10):1355. doi: 10.3390/biom12101355. Biomolecules. 2022. PMID: 36291564 Free PMC article. - Effects of treadmill training on functional recovery following peripheral nerve injury in rats.
Boeltz T, Ireland M, Mathis K, Nicolini J, Poplavski K, Rose SJ, Wilson E, English AW. Boeltz T, et al. J Neurophysiol. 2013 Jun;109(11):2645-57. doi: 10.1152/jn.00946.2012. Epub 2013 Mar 6. J Neurophysiol. 2013. PMID: 23468390 Free PMC article. - Functional and electron-microscopic changes after differential traction injury in the sciatic nerve of a rat.
Byun SH, Ahn KM. Byun SH, et al. Maxillofac Plast Reconstr Surg. 2021 May 1;43(1):12. doi: 10.1186/s40902-021-00297-4. Maxillofac Plast Reconstr Surg. 2021. PMID: 33934285 Free PMC article. - Bioactive Nanofiber-Based Conduits in a Peripheral Nerve Gap Management-An Animal Model Study.
Dębski T, Kijeńska-Gawrońska E, Zołocińska A, Siennicka K, Słysz A, Paskal W, Włodarski PK, Święszkowski W, Pojda Z. Dębski T, et al. Int J Mol Sci. 2021 May 25;22(11):5588. doi: 10.3390/ijms22115588. Int J Mol Sci. 2021. PMID: 34070436 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources