Isolation and sequencing of a cDNA clone encoding 107 kDa sialoglycoprotein in rat liver lysosomal membranes - PubMed (original) (raw)
Comparative Study
. 1989 Feb 27;244(2):351-6.
doi: 10.1016/0014-5793(89)80561-7.
Affiliations
- PMID: 2920835
- DOI: 10.1016/0014-5793(89)80561-7
Free article
Comparative Study
Isolation and sequencing of a cDNA clone encoding 107 kDa sialoglycoprotein in rat liver lysosomal membranes
M Himeno et al. FEBS Lett. 1989.
Free article
Abstract
A cDNA for 107 kDa sialoglycoprotein (LGP 107), the major protein component of rat liver lysosomal membranes, was isolated and sequenced. The 1.8 kbp cDNA contained an open reading frame encoding a polypeptide consisting of 386 amino acid residues (Mr 41,914). The deduced NH2-terminal 10-residue sequence is identical with that determined for purified LGP 107. The primary structure deduced for LGP 107 contains 20 potential N-glycosylation sites and exhibits 82.5, 43 and 60% sequence similarities to mouse LAMP-1, chicken LEP 100, and a 120-kDa human lysosomal glycoprotein, respectively. Among these lysosomal glycoproteins, the amino acid sequence of the putative transmembrane segment is highly conserved. Northern blot hybridization analysis identified a single species of LGP 107 mRNA (2.1 kbp in length) in rat liver, kidney, brain, lung, spleen, heart and pancreas, although its level in pancreas was very low.
Similar articles
- Isolation and sequencing of a cDNA clone encoding 96 kDa sialoglycoprotein in rat liver lysosomal membranes.
Noguchi Y, Himeno M, Sasaki H, Tanaka Y, Kono A, Sakaki Y, Kato K. Noguchi Y, et al. Biochem Biophys Res Commun. 1989 Nov 15;164(3):1113-20. doi: 10.1016/0006-291x(89)91784-1. Biochem Biophys Res Commun. 1989. PMID: 2590192 - Isolation and sequencing of a cDNA clone encoding 85kDa sialoglycoprotein in rat liver lysosomal membranes.
Fujita H, Ezaki J, Noguchi Y, Kono A, Himeno M, Kato K. Fujita H, et al. Biochem Biophys Res Commun. 1991 Jul 31;178(2):444-52. doi: 10.1016/0006-291x(91)90127-s. Biochem Biophys Res Commun. 1991. PMID: 1859403 - Isolation and sequencing of a cDNA clone encoding acid phosphatase in rat liver lysosomes.
Himeno M, Fujita H, Noguchi Y, Kono A, Kato K. Himeno M, et al. Biochem Biophys Res Commun. 1989 Aug 15;162(3):1044-53. doi: 10.1016/0006-291x(89)90779-1. Biochem Biophys Res Commun. 1989. PMID: 2764916 - Identification and characterization of a major lysosomal membrane glycoprotein, LGP85/LIMP II in mouse liver.
Tabuchi N, Akasaki K, Sasaki T, Kanda N, Tsuji H. Tabuchi N, et al. J Biochem. 1997 Oct;122(4):756-63. doi: 10.1093/oxfordjournals.jbchem.a021820. J Biochem. 1997. PMID: 9399579 - Biogenesis of the lysosomal membrane.
Fukuda M. Fukuda M. Subcell Biochem. 1994;22:199-230. doi: 10.1007/978-1-4615-2401-4_7. Subcell Biochem. 1994. PMID: 8146882 Review. No abstract available.
Cited by
- Expression of lysosome-associated membrane proteins in human colorectal neoplasms and inflammatory diseases.
Furuta K, Ikeda M, Nakayama Y, Nakamura K, Tanaka M, Hamasaki N, Himeno M, Hamilton SR, August JT. Furuta K, et al. Am J Pathol. 2001 Aug;159(2):449-55. doi: 10.1016/S0002-9440(10)61716-6. Am J Pathol. 2001. PMID: 11485903 Free PMC article. - Increased synthesis and specific localization of a major lysosomal membrane sialoglycoprotein (LGP107) at the ruffled border membrane of active osteoclasts.
Akamine A, Tsukuba T, Kimura R, Maeda K, Tanaka Y, Kato K, Yamamoto K. Akamine A, et al. Histochemistry. 1993 Aug;100(2):101-8. doi: 10.1007/BF00572895. Histochemistry. 1993. PMID: 8244761 - Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail.
Williams MA, Fukuda M. Williams MA, et al. J Cell Biol. 1990 Sep;111(3):955-66. doi: 10.1083/jcb.111.3.955. J Cell Biol. 1990. PMID: 2391371 Free PMC article. - Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane.
Harter C, Mellman I. Harter C, et al. J Cell Biol. 1992 Apr;117(2):311-25. doi: 10.1083/jcb.117.2.311. J Cell Biol. 1992. PMID: 1560028 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
Miscellaneous