A maximum likelihood map of chromosome 1 - PubMed (original) (raw)

A maximum likelihood map of chromosome 1

D C Rao et al. Am J Hum Genet. 1979 Nov.

Abstract

Thirteen loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a fourteenth locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1-AMY segment is uncertain. Eight other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.

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