Mind-altering with the gut: Modulation of the gut-brain axis with probiotics - PubMed (original) (raw)

Review

. 2018 Mar;56(3):172-182.

doi: 10.1007/s12275-018-8032-4. Epub 2018 Feb 28.

Affiliations

• PMID: 29492874
• DOI: 10.1007/s12275-018-8032-4

Review

Mind-altering with the gut: Modulation of the gut-brain axis with probiotics

Namhee Kim et al. J Microbiol. 2018 Mar.

Abstract

It is increasingly evident that bidirectional interactions exist among the gastrointestinal tract, the enteric nervous system, and the central nervous system. Recent preclinical and clinical trials have shown that gut microbiota plays an important role in these gut-brain interactions. Furthermore, alterations in gut microbiota composition may be associated with pathogenesis of various neurological disorders, including stress, autism, depression, Parkinson's disease, and Alzheimer's disease. Therefore, the concepts of the microbiota-gut-brain axis is emerging. Here, we review the role of gut microbiota in bidirectional interactions between the gut and the brain, including neural, immune-mediated, and metabolic mechanisms. We highlight recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders via the gut-brain axis.

Keywords: gut dysbiosis; gut microbiota; gutbrain axis; nervous system; neurological disorders; probiotics.

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References

1. 1. Nature. 2013 Dec 19;504(7480):446-50 - PubMed
2. 1. Gastroenterology. 2013 Jun;144(7):1394-401, 1401.e1-4 - PubMed
3. 1. Front Microbiol. 2016 Feb 17;7:185 - PubMed
4. 1. Biol Psychiatry. 2009 Feb 1;65(3):263-7 - PubMed
5. 1. PLoS One. 2011;6(12 ):e28032 - PubMed

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