Role of Langerhans cells in the infection of the guinea-pig epidermis with foot-and-mouth disease virus - PubMed (original) (raw)

Role of Langerhans cells in the infection of the guinea-pig epidermis with foot-and-mouth disease virus

W di Girolamo et al. Arch Virol. 1985.

Abstract

In guinea-pig infected with foot-and-mouth disease virus (FMDV), Langerhans cells in the foot pads increase in number and show viral antigens 24 hours post-inoculation, preceding appearance of virus in epithelial cells and vesiculation. This observation suggests that Langerhans cells may be engaged in virus transport from the blood to the non vascularized epidermis.

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