Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions - PubMed (original) (raw)
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions
D Gidoni et al. Science. 1985.
Abstract
The 21-base pair repeat elements of the SV40 promoter contain six tandem copies of the GGGCGG hexanucleotide (GC-box), each of which can bind, with varying affinity, to the cellular transcription factor, Sp1. In vitro SV40 early RNA synthesis is mediated by interaction of Sp1 with GC-boxes I, II, and III, whereas transcription in the late direction is mediated by binding to GC-boxes III, V, and VI.
Similar articles
- Binding of the Sp1 transcription factor by the human Harvey ras1 proto-oncogene promoter.
Ishii S, Kadonaga JT, Tjian R, Brady JN, Merlino GT, Pastan I. Ishii S, et al. Science. 1986 Jun 13;232(4756):1410-3. doi: 10.1126/science.3012774. Science. 1986. PMID: 3012774 - The enhancer elements and GGGCGG boxes of SV40 provide similar functions in bidirectionally promoting transcription.
Hertz GZ, Mertz JE. Hertz GZ, et al. Virology. 1988 Apr;163(2):579-90. doi: 10.1016/0042-6822(88)90299-1. Virology. 1988. PMID: 2833024 - Transcription factor Sp1 recognizes promoter sequences from the monkey genome that are simian virus 40 promoter.
Dynan WS, Saffer JD, Lee WS, Tjian R. Dynan WS, et al. Proc Natl Acad Sci U S A. 1985 Aug;82(15):4915-9. doi: 10.1073/pnas.82.15.4915. Proc Natl Acad Sci U S A. 1985. PMID: 2991898 Free PMC article. - Identification of a DNA structural motif that includes the binding sites for Sp1, p53 and GA-binding protein.
MacLeod MC. MacLeod MC. Nucleic Acids Res. 1993 Mar 25;21(6):1439-47. doi: 10.1093/nar/21.6.1439. Nucleic Acids Res. 1993. PMID: 8385318 Free PMC article. - Regulation of SV40 early gene expression.
Wildeman AG. Wildeman AG. Biochem Cell Biol. 1988 Jun;66(6):567-77. doi: 10.1139/o88-067. Biochem Cell Biol. 1988. PMID: 2844212 Review.
Cited by
- Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development.
McCoy AM, Lakhdari O, Shome S, Caoili K, Hernandez GE, Aghaeepour N, Butcher LD, Fisch K, Prince LS. McCoy AM, et al. Development. 2023 Mar 1;150(5):dev200839. doi: 10.1242/dev.200839. Epub 2023 Mar 3. Development. 2023. PMID: 36762637 Free PMC article. - Bidirectional promoter activity from expression cassettes can drive off-target repression of neighboring gene translation.
Powers EN, Chan C, Doron-Mandel E, Llacsahuanga Allcca L, Kim Kim J, Jovanovic M, Brar GA. Powers EN, et al. Elife. 2022 Dec 12;11:e81086. doi: 10.7554/eLife.81086. Elife. 2022. PMID: 36503721 Free PMC article. - A Novel SNP in the Promoter Region of IGF1 Associated With Yunshang Black Goat Kidding Number via Promoting Transcription Activity by SP1.
Li K, Liu Y, He X, Tao L, Jiang Y, Lan R, Hong Q, Chu M. Li K, et al. Front Cell Dev Biol. 2022 May 12;10:873095. doi: 10.3389/fcell.2022.873095. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35646903 Free PMC article. - CGGBP1-dependent CTCF-binding sites restrict ectopic transcription.
Patel D, Patel M, Datta S, Singh U. Patel D, et al. Cell Cycle. 2021 Nov;20(22):2387-2401. doi: 10.1080/15384101.2021.1982508. Epub 2021 Sep 29. Cell Cycle. 2021. PMID: 34585631 Free PMC article. - Regulation of arsenic methylation: identification of the transcriptional region of the human AS3MT gene.
Yoshinaga-Sakurai K, Rossman TG, Rosen BP. Yoshinaga-Sakurai K, et al. Cell Biol Toxicol. 2022 Oct;38(5):765-780. doi: 10.1007/s10565-021-09611-2. Epub 2021 May 6. Cell Biol Toxicol. 2022. PMID: 33956289 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
Miscellaneous