Stevia Leaf to Stevia Sweetener: Exploring Its Science, Benefits, and Future Potential - PubMed (original) (raw)
Review
. 2018 Jul 1;148(7):1186S-1205S.
doi: 10.1093/jn/nxy102.
Affiliations
- PMID: 29982648
- DOI: 10.1093/jn/nxy102
Free article
Review
Stevia Leaf to Stevia Sweetener: Exploring Its Science, Benefits, and Future Potential
Priscilla Samuel et al. J Nutr. 2018.
Free article
Abstract
Steviol glycoside sweeteners are extracted and purified from the Stevia rebaudiana Bertoni plant, a member of the Asteraceae (Compositae) family that is native to South America, where it has been used for its sweet properties for hundreds of years. With continued increasing rates of obesity, diabetes, and other related comorbidities, in conjunction with global public policies calling for reductions in sugar intake as a means to help curb these issues, low- and no-calorie sweeteners (LNCSs, also known as high-potency sweeteners) such as stevia are gaining interest among consumers and food manufacturers. This appeal is related to stevia being plant-based, zero calorie and with a sweet taste that is 50-350 times sweeter than sugar, making it an excellent choice for use in sugar- and calorie-reduced food and beverage products. Despite the fact that the safety of stevia has been affirmed by several food regulatory and safety authorities around the world, insufficient education about stevia's safety and benefits, including continuing concern with regard to the safety of LNCSs in general, deters health professionals and consumers from recommending or using stevia. Therefore, the aim of this review and the stevia symposium that preceded this review at the ASN's annual conference in 2017 was to examine, in a comprehensive manner, the state of the science for stevia, its safety and potential health benefits, and future research and application. Topics covered included metabolism, safety and acceptable intake, dietary exposure, impact on blood glucose and insulin concentrations, energy intake and weight management, blood pressure, dental caries, naturality and processing, taste and sensory properties, regulatory status, consumer insights, and market trends. Data for stevia are limited in the case of energy intake and weight management as well as for the gut microbiome; therefore, the broader literature on LNCSs was reviewed at the symposium and therefore is also included in this review.
Similar articles
- Steviol glycoside safety: are highly purified steviol glycoside sweeteners food allergens?
Urban JD, Carakostas MC, Taylor SL. Urban JD, et al. Food Chem Toxicol. 2015 Jan;75:71-8. doi: 10.1016/j.fct.2014.11.011. Epub 2014 Nov 18. Food Chem Toxicol. 2015. PMID: 25449199 Review. - FDA regulatory approach to steviol glycosides.
Perrier JD, Mihalov JJ, Carlson SJ. Perrier JD, et al. Food Chem Toxicol. 2018 Dec;122:132-142. doi: 10.1016/j.fct.2018.09.062. Epub 2018 Sep 27. Food Chem Toxicol. 2018. PMID: 30268795 - Anti-Quorum Sensing Activity of Stevia Extract, Stevioside, Rebaudioside A and Their Aglycon Steviol.
Markus V, Share O, Teralı K, Ozer N, Marks RS, Kushmaro A, Golberg K. Markus V, et al. Molecules. 2020 Nov 23;25(22):5480. doi: 10.3390/molecules25225480. Molecules. 2020. PMID: 33238612 Free PMC article. - A Review on the Pharmacology and Toxicology of Steviol Glycosides Extracted from Stevia rebaudiana.
Momtazi-Borojeni AA, Esmaeili SA, Abdollahi E, Sahebkar A. Momtazi-Borojeni AA, et al. Curr Pharm Des. 2017;23(11):1616-1622. doi: 10.2174/1381612822666161021142835. Curr Pharm Des. 2017. PMID: 27784241 Review. - Properties, extraction and purification technologies of Stevia rebaudiana steviol glycosides: A review.
Huang C, Wang Y, Zhou C, Fan X, Sun Q, Han J, Hua C, Li Y, Niu Y, Emeka Okonkwo C, Yao D, Song L, Otu P. Huang C, et al. Food Chem. 2024 Sep 30;453:139622. doi: 10.1016/j.foodchem.2024.139622. Epub 2024 May 17. Food Chem. 2024. PMID: 38761729 Review.
Cited by
- Fabrication and characterization of cocoa butter-based caffeine fast-melting tablets.
Janakiraman AK, Yap J, Sundarapandian R, Liew KB, Subramaniyan V, Kayarohanam S. Janakiraman AK, et al. Ther Deliv. 2024;15(7):495-505. doi: 10.1080/20415990.2024.2354115. Epub 2024 Jun 11. Ther Deliv. 2024. PMID: 38888592 - Influence of the Nitrogen Fertilization on the Yield, Biometric Characteristics and Chemical Composition of Stevia rebaudiana Bertoni Grown in Poland.
Śniegowska J, Biesiada A, Gasiński A. Śniegowska J, et al. Molecules. 2024 Apr 19;29(8):1865. doi: 10.3390/molecules29081865. Molecules. 2024. PMID: 38675686 Free PMC article. - An Apple and Acáchul Berry Snack Rich in Bioaccessible Antioxidants and Folic Acid: A Healthy Alternative for Prenatal Diets.
Corfield R, Allievi MC, Rivero R, López TA, Pérez OE, Salvatori D, Schebor C. Corfield R, et al. Foods. 2024 Feb 24;13(5):692. doi: 10.3390/foods13050692. Foods. 2024. PMID: 38472805 Free PMC article. - Stevia rebaudiana Bertoni, an American plant used as sweetener: Study of its effects on body mass control and glycemia reduction in Wistar male and female rats.
Mendoza-Pérez S, Orta-Méndez-Y-Sánchez I, García-Gómez RS, Ordaz-Nava G, Gracia-Mora MI, Macías-Rosales L, Rico-Morales HA, Salas-Garrido G, Durán-Domínguez-de-Bazúa MDC. Mendoza-Pérez S, et al. PLoS One. 2024 Feb 27;19(2):e0298251. doi: 10.1371/journal.pone.0298251. eCollection 2024. PLoS One. 2024. PMID: 38412182 Free PMC article. - Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity.
Morissette A, de Wouters d'Oplinter A, Andre DM, Lavoie M, Marcotte B, Varin TV, Trottier J, Pilon G, Pelletier M, Cani PD, Barbier O, Houde VP, Marette A. Morissette A, et al. Sci Rep. 2024 Feb 6;14(1):3077. doi: 10.1038/s41598-024-53587-y. Sci Rep. 2024. PMID: 38321177 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources