Homology between the photoreactivation genes of Saccharomyces cerevisiae and Escherichia coli - PubMed (original) (raw)

Comparative Study

Homology between the photoreactivation genes of Saccharomyces cerevisiae and Escherichia coli

A Yasui et al. Gene. 1985.

Abstract

A cloned fragment of Saccharomyces cerevisiae chromosomal DNA carrying the photoreactivation gene (PHR) has been sequenced. The fragment contains a 1695-bp intronless open reading frame (ORF) coding for a polypeptide of 564 amino acids (aa). The phr gene of Escherichia coli was also sequenced, and the sequence is in agreement with the published data. The yeast PHR gene has a G + C content of 36.2%, whereas 53.7% was found for the E. coli gene. Despite the difference in G + C content there is a 35% homology between the deduced aa sequences. This homology suggests that both genes have originated from a common ancestral gene.

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