The molecular heterogeneity of protein kinase C and its implications for cellular regulation - PubMed (original) (raw)

Review

. 1988 Aug 25;334(6184):661-5.

doi: 10.1038/334661a0.

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• PMID: 3045562
• DOI: 10.1038/334661a0

Review

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

Y Nishizuka. Nature. 1988.

Abstract

Protein kinase C is now known to be a large family of proteins, with multiple subspecies that have subtle individual enzymological characteristics. Some members of the family exhibit distinct patterns of tissue expression and intracellular localization; different kinases probably have distinct functions in the processing and modulation of a variety of physiological and pathological responses to external signals.

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