Hepatocellular carcinoma: resection with adjuvant hepatic artery infusion therapy vs resection alone. A systematic review and meta-analysis - PubMed (original) (raw)

Meta-Analysis

. 2019 Mar;119(4):455-463.

doi: 10.1002/jso.25338. Epub 2018 Dec 21.

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Meta-Analysis

Hepatocellular carcinoma: resection with adjuvant hepatic artery infusion therapy vs resection alone. A systematic review and meta-analysis

Alexandra Moran et al. J Surg Oncol. 2019 Mar.

Abstract

Hepatocellular carcinoma (HCC) has a recurrence rate of up to 70% in 5 years after resection, detrimentally lowering survival. The role of adjuvant therapy remains controversial; therefore, the aim of this study was to evaluate the disease-free and overall survival of patients with HCC, not candidates for transplantation, undergoing resection and adjuvant hepatic artery infusion therapy vs resection alone. Our meta-analysis showed that adjuvant HAIC improves overall and disease-free survival after resection, especially in tumors ≥7 cm.

Keywords: adjuvant hepatic artery infusion therapy (HAIT); hepatocellular carcinoma (HCC); resection.

© 2018 Wiley Periodicals, Inc.

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