Diazepam - PubMed (original) (raw)

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In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.

2023 Aug 28.

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• PMID: 30725707
• Bookshelf ID: NBK537022

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Diazepam

Jaberpreet S. Dhaliwal et al.

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Excerpt

Diazepam is a benzodiazepine medication that is FDA approved for the management of anxiety disorders, short-term relief of anxiety symptoms, spasticity associated with upper motor neuron disorders, adjunct therapy for muscle spasms, preoperative anxiety relief, management of certain refractory epilepsy patients, and adjunct in severe recurrent convulsive seizures, and an adjunct in status epilepticus. Off-label (non-FDA approved) use for diazepam includes sedation in the ICU and short-term treatment of spasticity in children with cerebral palsy. This activity will highlight the mechanism of action, adverse event profile, approved and off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, and relevant interactions of diazepam, pertinent for interprofessional team members using diazepam for any of its intended indications.

Copyright © 2024, StatPearls Publishing LLC.

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Conflict of interest statement

Disclosure: Jaberpreet Dhaliwal declares no relevant financial relationships with ineligible companies.

Disclosure: Alan Rosani declares no relevant financial relationships with ineligible companies.

Disclosure: Abdolreza Saadabadi declares no relevant financial relationships with ineligible companies.

Sections

• Continuing Education Activity
• Indications
• Mechanism of Action
• Administration
• Adverse Effects
• Contraindications
• Monitoring
• Toxicity
• Enhancing Healthcare Team Outcomes
• Review Questions
• References

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