The central amygdala and immobilization stress-induced gastric pathology in rats: neurotensin and dopamine - PubMed (original) (raw)
The central amygdala and immobilization stress-induced gastric pathology in rats: neurotensin and dopamine
A Ray et al. Brain Res. 1987.
Abstract
Bilateral microinjections of neurotensin (3, 10 and 30 micrograms) into the central amygdala had a dose-related attenuating effect on cold-restraint gastric ulcers in rats. Similar inhibitory effects were also observed with intra-amygdalar dopamine (3, 10 and 30 micrograms). Pretreatment with 6-hydroxydopamine (10 micrograms) or haloperidol (1 mg/kg), however, reversed the ulcer attenuating effect of neurotensin. The results indicate that the central amygdala is important in the mediation of the cytoprotective effects of neurotensin and dopamine.