A new class of yeast transcriptional activators - PubMed (original) (raw)
Comparative Study
A new class of yeast transcriptional activators
J Ma et al. Cell. 1987.
Abstract
We describe yeast transcriptional activators encoded by E. coli genomic DNA fragments fused to the coding sequence of the DNA-binding portion of GAL4. All of the new activating sequences that we have analyzed, like those of GAL4 and GCN4, are acidic; most of these sequences show no obvious sequence homology when compared with the identified activating regions of GAL4 and GCN4 or among themselves. We also describe a fusion protein that contains no yeast protein sequence but activates transcription in yeast.
Comment in
- Two "what if" experiments.
Ptashne M. Ptashne M. Cell. 2004 Jan 23;116(2 Suppl):S71-2, 2 p following S76. doi: 10.1016/s0092-8674(03)01076-6. Cell. 2004. PMID: 15055587 No abstract available. - Actively seeking activating sequences.
Ma J. Ma J. Cell. 2004 Jan 23;116(2 Suppl):S75-6, 2 p following S76. doi: 10.1016/s0092-8674(03)01033-x. Cell. 2004. PMID: 15055589 No abstract available.
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