Spinal cord repair: advances in biology and technology - PubMed (original) (raw)

Review

. 2019 Jun;25(6):898-908.

doi: 10.1038/s41591-019-0475-6. Epub 2019 Jun 3.

Affiliations

• PMID: 31160817
• DOI: 10.1038/s41591-019-0475-6

Review

Spinal cord repair: advances in biology and technology

Grégoire Courtine et al. Nat Med. 2019 Jun.

Abstract

Individuals with spinal cord injury (SCI) can face decades with permanent disabilities. Advances in clinical management have decreased morbidity and improved outcomes, but no randomized clinical trial has demonstrated the efficacy of a repair strategy for improving recovery from SCI. Here, we summarize recent advances in biological and engineering strategies to augment neuroplasticity and/or functional recovery in animal models of SCI that are pushing toward clinical translation.

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