Infectious lymphocytes in lymphocytic choriomeningitis virus carrier mice - PubMed (original) (raw)
Infectious lymphocytes in lymphocytic choriomeningitis virus carrier mice
M Popescu et al. J Gen Virol. 1979 Mar.
Abstract
The infectivity of blood and lymphoid organs of mice persistently infected with lymphocytic choriomeningitis virus was found to be predominantly associated with lymphocytes and both T and B cells were infectious. A hypothesis is presented in which it is assumed that lymphocytes in carrier mice are infected via their LCM virus-specific antigen receptors, thereby leading to their antigen-triggered clonal expansion followed by infection and functional inactivation.
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