Recent advances in mammalian reproductive biology - PubMed (original) (raw)

Review

doi: 10.1007/s11427-019-1572-7. Epub 2019 Nov 29.

Qiang Liu 1, Jingjing Xu 2, Xixi Liu 1, Chaoyi Shi 2, Zuwei Yang 2, Yili Zhang 2, Hong Xu 2, Jiang Liu 3, Hui Yang 4, Hefeng Huang 5, Jie Qiao 6, Fuchou Tang 7, Zi-Jiang Chen 8

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Review

Recent advances in mammalian reproductive biology

Lu Wen et al. Sci China Life Sci. 2020 Jan.

Abstract

Reproductive biology is a uniquely important topic since it is about germ cells, which are central for transmitting genetic information from generation to generation. In this review, we discuss recent advances in mammalian germ cell development, including preimplantation development, fetal germ cell development and postnatal development of oocytes and sperm. We also discuss the etiologies of female and male infertility and describe the emerging technologies for studying reproductive biology such as gene editing and single-cell technologies.

Keywords: female infertility; fetal germ cell; gene editing; male infertility; oogenesis; preimplantation; single-cell sequencing; spermatogenesis.

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References

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