Exercise for the intervertebral disc: a 6-month randomised controlled trial in chronic low back pain - PubMed (original) (raw)

Randomized Controlled Trial

. 2020 Aug;29(8):1887-1899.

doi: 10.1007/s00586-020-06379-7. Epub 2020 Mar 24.

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Randomized Controlled Trial

Exercise for the intervertebral disc: a 6-month randomised controlled trial in chronic low back pain

Patrick J Owen et al. Eur Spine J. 2020 Aug.

Abstract

Background context: Muscle, bone and tendon respond anabolically to mechanical forces. Whether the intervertebral disc (IVD) can benefit from exercise is unclear.

Purpose: To examine whether exercise can beneficially affect IVD characteristics.

Study design/setting: This is a single-blinded 6-month randomised controlled trial (ACTRN12615001270505) in an exercise and physiotherapy clinic.

Patient sample: Forty patients with chronic non-specific low back pain (NSCLBP) are included in this study.

Outcome measures: The primary outcome was lumbar IVD T2 time (MRI). Secondary outcomes included IVD diffusion coefficient and IVD expansion with short-duration lying.

Methods: Twenty patients progressively loaded their lumbar IVDs (exercise) via an exercise programme involving progressive upright aerobic and resistance exercises targeting the trunk and major muscle groups and were compared to twenty patients who performed motor control training and manual therapy (control). Testing occurred at baseline, 3 months and 6 months.

Results: Seventeen exercise and fifteen control patients completed the interventions. There were no group-by-time differences in T2 time of the entire IVD (exercise 94.1 ± 10.0 ms vs. control 96.5 ± 9.3 ms, p = 0.549). Exercise patients had shorter T2 time in the posterior annulus at 6 months (82.7 ± 6.8 ms vs. 85.1 ± 8.0 ms, p = 0.028). Exercise patients showed higher L5/S1 apparent diffusion coefficients and decreased IVD height at 3 months (both p ≤ 0.050). After adjustments for multiple comparisons, differences lost statistical significance. Per-protocol and intent-to-treat analyses yielded similar findings.

Conclusions: This trial found that 6 months of exercise did not benefit the IVD of people with NSCLBP. Based on this index study, future studies could investigate the effect of exercise on IVD in different populations, with different types, durations and/or intensities of exercise, and using different IVD markers. These slides can be retrieved under Electronic Supplementary Material.

Keywords: Intervertebral disc; Magnetic resonance imaging; Physical activity; Physical therapy; Physiotherapy; Rehabilitation; Spine.

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References

    1. Hawley JA (2008) Specificity of training adaptation: Time for a rethink? J Physiol 586:1–2 - PubMed - PMC
    1. Wolff J (1892) The law of bone remodeling (Das gesetz der transformation der knochen). Springer, Berlin
    1. Schoenfeld BJ, Ogborn D, Krieger JW (2016) Effects of resistance training frequency on measures of muscle hypertrophy: a systematic review and meta-analysis. Sports Med 46:1689–1697 - PubMed
    1. Polidoulis I, Beyene J, Cheung A (2012) The effect of exercise on pQCT parameters of bone structure and strength in postmenopausal women—A systematic review and meta-analysis of randomized controlled trials. Osteoporos Int 23:39–51 - PubMed
    1. Marques EA, Mota J, Carvalho J (2012) Exercise effects on bone mineral density in older adults: a meta-analysis of randomized controlled trials. Age 34:1493–1515 - PubMed

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