On measures of gametic disequilibrium - PubMed (original) (raw)
On measures of gametic disequilibrium
R C Lewontin. Genetics. 1988 Nov.
Abstract
Various measures have been proposed for characterizing the statistical association that arises between alleles at different loci. Hedrick has compared these measures with the standardized measure D' proposed by Lewontin on the grounds that this latter measure is independent of allele frequency. Although D' has the same range for all allelic frequencies, in fact, D' is not "independent" of allele frequency, and no measure with that general property is possible for the multilocus association problem. The insolubility of this problem arises from the ill-defined nature of general "association."
Similar articles
- The D' measure of overall gametic disequilibrium between pairs of multiallelic loci.
Zapata C. Zapata C. Evolution. 2000 Oct;54(5):1809-12. Evolution. 2000. PMID: 11108607 - Inference of recombinational hotspots using gametic disequilibrium values.
Hedrick PW. Hedrick PW. Heredity (Edinb). 1988 Jun;60 ( Pt 3):435-8. doi: 10.1038/hdy.1988.61. Heredity (Edinb). 1988. PMID: 3417475 - Gametic disequilibrium measures: proceed with caution.
Hedrick PW. Hedrick PW. Genetics. 1987 Oct;117(2):331-41. doi: 10.1093/genetics/117.2.331. Genetics. 1987. PMID: 3666445 Free PMC article. - Sampling variance and distribution of the D' measure of overall gametic disequilibrium between multiallelic loci.
Zapata C, Carollo C, Rodriguez S. Zapata C, et al. Ann Hum Genet. 2001 Jul;65(Pt 4):395-406. doi: 10.1017/S0003480001008697. Ann Hum Genet. 2001. PMID: 11592929 - The theory of speciation via the founder principle.
Templeton AR. Templeton AR. Genetics. 1980 Apr;94(4):1011-38. doi: 10.1093/genetics/94.4.1011. Genetics. 1980. PMID: 6777243 Free PMC article. Review.
Cited by
- An orthology-based methodology as a complementary approach to retrieve evolutionarily conserved A-to-I RNA editing sites.
Liu J, Zhao T, Zheng C, Ma L, Song F, Tian L, Cai W, Li H, Duan Y. Liu J, et al. RNA Biol. 2024 Jan;21(1):29-45. doi: 10.1080/15476286.2024.2397757. Epub 2024 Sep 10. RNA Biol. 2024. PMID: 39256954 Free PMC article. - Polygenic selection to a changing optimum under self-fertilisation.
Hartfield M, Glémin S. Hartfield M, et al. PLoS Genet. 2024 Jul 17;20(7):e1011312. doi: 10.1371/journal.pgen.1011312. eCollection 2024 Jul. PLoS Genet. 2024. PMID: 39018328 Free PMC article. - IGF2BP2 and IGFBP3 Genotypes, Haplotypes, and Genetic Models Studies in Polycystic Ovary Syndrome.
Govahi Kakhki F, Sargazi S, Montazerifar F, Majidpour M, Karajibani A, Karajibani M, Ghasemi M. Govahi Kakhki F, et al. J Clin Lab Anal. 2024 Mar;38(5):e25021. doi: 10.1002/jcla.25021. Epub 2024 Mar 11. J Clin Lab Anal. 2024. PMID: 38468402 Free PMC article. - Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species.
Daigle A, Johri P. Daigle A, et al. bioRxiv [Preprint]. 2024 Sep 23:2024.02.06.579142. doi: 10.1101/2024.02.06.579142. bioRxiv. 2024. PMID: 38370745 Free PMC article. Preprint. - Natural selection and genetic diversity maintenance in a parasitic wasp during continuous biological control application.
Li B, Duan Y, Du Z, Wang X, Liu S, Feng Z, Tian L, Song F, Yang H, Cai W, Lin Z, Li H. Li B, et al. Nat Commun. 2024 Feb 14;15(1):1379. doi: 10.1038/s41467-024-45631-2. Nat Commun. 2024. PMID: 38355730 Free PMC article.
References
- Genetics. 1964 Jan;49(1):49-67 - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources