T cells engineered to target senescence - PubMed (original) (raw)

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T cells engineered to target senescence

Verena Wagner et al. Nature. 2020 Jul.

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Keywords: Cancer; Immunology.

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• Senolytic CAR T cells reverse senescence-associated pathologies.
  Amor C, Feucht J, Leibold J, Ho YJ, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, Peerschke E, Friedman SL, Ponomarev V, Piersigilli A, Sadelain M, Lowe SW. Amor C, et al. Nature. 2020 Jul;583(7814):127-132. doi: 10.1038/s41586-020-2403-9. Epub 2020 Jun 17. Nature. 2020. PMID: 32555459 Free PMC article.

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