Avoiding harm: Tackling problematic polypharmacy through strengthening expert generalist practice - PubMed (original) (raw)
Review
doi: 10.1111/bcp.14531. Epub 2020 Sep 9.
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- PMID: 32840868
- DOI: 10.1111/bcp.14531
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Review
Avoiding harm: Tackling problematic polypharmacy through strengthening expert generalist practice
Joanne Reeve. Br J Clin Pharmacol. 2021 Jan.
Free article
Abstract
Problematic polypharmacy is a growing challenge. Medication that is intended to improve patients' health and wellbeing is instead becoming part of the problem. The way we practice medicine has become a driver for the problem. Dealing with the challenge will need us to think differently about how we do clinical care. A 2013 Kings Fund report stated that tackling problematic polypharmacy requires us to actively build a principle of compromise into the way we use medicines. There are implications for how we consult and make decisions with patients, in how we design health practice and systems to support that decision making, and, in our understanding of the process of research, how we generate the knowledge that informs practice. This review considers the current state of play in all 3 areas and identifies some of the work we still need to do in order to generate the practice-based evidence needed to tackle this most challenging problem. Finding a way to redesign practice to address problematic polypharmacy could offer a template for tackling other related complex issues facing medical practice such as multimorbidity, chronic pain and complex mental health.
Keywords: generalism; multimorbidity; polypharmacy; problematic polypharmacy.
© 2020 The British Pharmacological Society.
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References
REFERENCES
- Duerden M, Avery T, Payne R. Polypharmacy and medicines optimisation. Making it safe and sound https://www.kingsfund.org.uk/sites/default/files/field/field_publication... (accessed 30 July 2020).
- EDeN: English Deprescribing Network Briefing. April 2019. https://www.sps.nhs.uk/articles/english-deprescribing-network-resource-p... (accessed 30 July 2020)
- Payne RA, Abel GA, Avery AJ, Mercer SW, Mo R. Is polypharmacy always hazardous? A retrospective cohort analysis using linked electronic health records from primary and secondary care. Br J Clin Pharmacol. 2014;77(6):1073-1082.
- Krska J, Katusiime B, Corlett SA. Patient experiences of the burden of using medicines for long-term conditions and factors affecting burden: a cross-sectional survey. Health Soc Care Community. 2018;26(6):946-959.
- NHS England. Medicines Optimisation. https://www.england.nhs.uk/medicines-2/medicines-optimisation/ (accessed 6 June 2020)
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