Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients. A new model for the quantitation and follow-up of preclinical atherosclerosis in living human subjects - PubMed (original) (raw)
Ultrasonographic measurement of the common carotid artery wall thickness in hypercholesterolemic patients. A new model for the quantitation and follow-up of preclinical atherosclerosis in living human subjects
A Poli et al. Atherosclerosis. 1988 Apr.
Abstract
Ultrasound high resolution B-mode imaging of human arteries allows in vivo an accurate and non-invasive determination of the thickness of the intimal-medial complex. A computer assisted procedure to measure this parameter at the level of common carotid arteries was developed. The average difference between duplicate thickness determinations was 4.6%. The thickness of the intimal medial complex of common carotid arteries was then measured in a group of hypercholesterolemic patients. This parameter was significantly greater in these patients as compared to controls (P less than 0.001). The prevalence of small plaques in the carotid arterial tree was also significantly increased in patients. Analysis of data showed that in controls, but not in patients, the thickness of the intimal medial complex increases with age (r = 0.46, P less than 0.05). Within the hypercholesterolemic group, intimal-medial complex values were greater in male patients and in smokers. It is concluded that the common carotid arteries of hypercholesterolemic patients show thickening of the intimal-medial complex. Cigarette smoking, male sex and age increase the extent of this modification. The determination of this parameter using a non-invasive technique may represent an important tool to monitor in vivo the progression and/or the regression of early atherosclerosis in man.
Similar articles
- Early carotid atherosclerosis in healthy middle-aged women. A follow-up study.
Bonithon-Kopp C, Jouven X, Taquet A, Touboul PJ, Guize L, Scarabin PY. Bonithon-Kopp C, et al. Stroke. 1993 Dec;24(12):1837-43. doi: 10.1161/01.str.24.12.1837. Stroke. 1993. PMID: 8248965 - Carotid intimal-medial thickness and stiffness are not affected by hypercholesterolemia in uncomplicated essential hypertension.
Saba PS, Roman MJ, Longhini C, Scorzoni D, Pini R, Devereux RB, Ganau A. Saba PS, et al. Arterioscler Thromb Vasc Biol. 1999 Nov;19(11):2788-94. doi: 10.1161/01.atv.19.11.2788. Arterioscler Thromb Vasc Biol. 1999. PMID: 10559027 - Associations of risk factors with segment-specific intimal-medial thickness of the extracranial carotid artery.
Espeland MA, Tang R, Terry JG, Davis DH, Mercuri M, Crouse JR 3rd. Espeland MA, et al. Stroke. 1999 May;30(5):1047-55. doi: 10.1161/01.str.30.5.1047. Stroke. 1999. PMID: 10229743 - Intimal-medial thickness of the common carotid arteries and lower limbs atherosclerosis in the elderly.
Mattace Raso F, Rosato M, Talerico A, Cotronei P, Mattace R. Mattace Raso F, et al. Minerva Cardioangiol. 1999 Oct;47(10):321-7. Minerva Cardioangiol. 1999. PMID: 10670252 Review. English, Italian. - [Intima media thickness of the carotid arteries: early pointer to arteriosclerosis and therapeutic endpoint].
Ludwig M, von Petzinger-Kruthoff A, von Buquoy M, Stumpe KO. Ludwig M, et al. Ultraschall Med. 2003 Jun;24(3):162-74. doi: 10.1055/s-2003-40058. Ultraschall Med. 2003. PMID: 12817310 Review. German.
Cited by
- Present and future of coronary risk assessment.
Prati F, Biccirè FG, Budassi S. Prati F, et al. Eur Heart J Suppl. 2021 Oct 8;23(Suppl E):E123-E127. doi: 10.1093/eurheartj/suab106. eCollection 2021 Oct. Eur Heart J Suppl. 2021. PMID: 34650370 Free PMC article. - Ultrasound Methods in the Evaluation of Atherosclerosis: From Pathophysiology to Clinic.
Cismaru G, Serban T, Tirpe A. Cismaru G, et al. Biomedicines. 2021 Apr 13;9(4):418. doi: 10.3390/biomedicines9040418. Biomedicines. 2021. PMID: 33924492 Free PMC article. Review. - Comparison of the Relation of Carotid Intima-Media Thickness With Incident Heart Failure With Reduced Versus Preserved Ejection Fraction (from the Multi-Ethnic Study of Atherosclerosis [MESA]).
Aladin AI, Soliman EZ, Kitzman DW, Dardari Z, Rasool SH, Yeboah J, Budoff MJ, Psaty BM, Ouyang P, Polak JF, Blumenthal RS, McEvoy JW, Gandhi SK, Herrington DM. Aladin AI, et al. Am J Cardiol. 2021 Jun 1;148:102-109. doi: 10.1016/j.amjcard.2021.02.020. Epub 2021 Mar 3. Am J Cardiol. 2021. PMID: 33667446 Free PMC article. - ANGPTL8 Gene Polymorphism rs2278426 Is Related to Carotid Intima-Media Thickness in T2DM.
Guo C, Zhao L, Ding Y, Zhao Z, Wang C, Li L, Cai Z, Li Y, Xia H, Zhu Z, Yu F, Dai M, Deng X, Yuan G. Guo C, et al. Diabetes Metab Syndr Obes. 2020 Nov 20;13:4519-4528. doi: 10.2147/DMSO.S274759. eCollection 2020. Diabetes Metab Syndr Obes. 2020. PMID: 33244249 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical