Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19 - PubMed (original) (raw)

doi: 10.1016/j.jinf.2020.08.029. Epub 2020 Aug 25.

Paul Janvier 2, Yousra Kherabi 1, Audrey Le Bot 1, Antoine Hamon 1, Hélène Gouze 1, Lucile Doucet 1, Sabryne Berkani 1, Emma Oliosi 1, Elise Mallart 1, Félix Corre 1, Virginie Zarrouk 1, Jean-Denis Moyer 3, Adrien Galy 1, Vasco Honsel 1, Bruno Fantin 1, Yann Nguyen 4

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Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19

Eve Garrigues et al. J Infect. 2020 Dec.

Abstract

Objective: To assess post-discharge persistent symptoms and health-related quality of life (HRQoL) of patients hospitalized in a COVID-19 ward unit more than 100 days after their admission.

Methods: All eligible patients were contacted by phone by trained physicians and were asked to answer to a dedicated questionnaire. Patients managed in hospital ward without needing intensive care were compared with those who were transferred in intensive care units (ICU).

Results: We included 120 patients after a mean (±SD) of 110.9 (±11.1) days following admission. The most frequently reported persistent symptoms were fatigue (55%), dyspnoea (42%), loss of memory (34%), concentration and sleep disorders (28% and 30.8%, respectively). Comparisons between ward- and ICU patients led to no statistically significant differences regarding those symptoms. In both group, EQ-5D (mobility, self-care, pain, anxiety or depression, usual activity) was altered with a slight difference in pain in the ICU group.

Conclusion: Most patients requiring hospitalization for COVID-19 still have persistent symptoms. While there were few differences between HRQoL between ward and ICU patients, our findings must be confirmed in larger cohorts, including more severe patients.

Keywords: Covid-19; Health-related quality of life; Persistent symptoms.

Copyright © 2020. Published by Elsevier Ltd.

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Conflict of interest statement

Declaration of Competing Interest None of the authors declared any competing interest in link with the present study.

Figures

Fig. 1

Fig. 1

Health-related quality of life after hospitalization for COVID-19 assessed by the EQ-5D 5 L in the ward and the ICU groups. 1A: Distribution of the EQ-5D index (0: death to 1: full health). 1B: EQ-5D 5 L scores in the ward and in the ICU groups on each domain. Each domain is scored on a 5-point scale: 1 no problem, 2 slight problem, 3 moderate problem, 4 severe problem, 5 unable to do. *: P = 0.032.

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