Restrictive Versus Liberal Transfusion Trials: Are They Asking the Right Question? - PubMed (original) (raw)

Comparative Study

. 2020 Dec;131(6):1950-1955.

doi: 10.1213/ANE.0000000000005227.

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Comparative Study

Restrictive Versus Liberal Transfusion Trials: Are They Asking the Right Question?

Kevin M Trentino et al. Anesth Analg. 2020 Dec.

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References

    1. Trentino KM, Farmer SL, Leahy MF, et al. Systematic reviews and meta-analyses comparing mortality in restrictive and liberal haemoglobin thresholds for red cell transfusion: an overview of systematic reviews. BMC Med. 2020;18:154.
    1. Trentino K, Farmer S, Gross I, Shander A, Isbister J. Observational studies - should we simply ignore them in assessing transfusion outcomes? BMC Anesthesiol. 2016;16:96.
    1. Mazer CD, Whitlock RP, Fergusson DA, et al.; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group. Restrictive or liberal red-cell transfusion for cardiac surgery. N Engl J Med. 2017;377:2133–2144.
    1. Grover M, Talwalkar S, Casbard A, et al. Silent myocardial ischaemia and haemoglobin concentration: a randomized controlled trial of transfusion strategy in lower limb arthroplasty. Vox Sang. 2006;90:105–112.
    1. So-Osman C, Nelissen R, Te Slaa R, Coene L, Brand R, Brand A. A randomized comparison of transfusion triggers in elective orthopaedic surgery using leucocyte-depleted red blood cells. Vox Sang. 2010;98:56–64.

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