Vitamin E Toxicity - PubMed (original) (raw)
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In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
2023 Feb 13.
- PMID: 33232043
- Bookshelf ID: NBK564373
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Vitamin E Toxicity
Kristen N. Owen et al.
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Excerpt
Vitamin E is a major lipid-soluble antioxidant obtained exclusively from the diet. It was discovered in the 1920s as an essential dietary element required by rats for reproduction. There are approximately 8 vitamin E-related molecules, but alpha-tocopherol is the dominant molecule in humans. Tocotrienols are the other molecules that are widely studied for vitamin E supplementation. These 2 molecules have been studied in various dosages and for various health purposes. Vitamin E has peroxyl radical scavenger properties. While vitamin E toxicity is associated with an increased risk of bleeding, its deficiency has been associated with neurologic diseases and anemia.
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Conflict of interest statement
Disclosure: Kristen Owen declares no relevant financial relationships with ineligible companies.
Disclosure: Olga Dewald declares no relevant financial relationships with ineligible companies.
Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Prognosis
- Complications
- Deterrence and Patient Education
- Pearls and Other Issues
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
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