A mismatch repair-based model can explain some features of u.v. mutagenesis in yeast - PubMed (original) (raw)

Review

A mismatch repair-based model can explain some features of u.v. mutagenesis in yeast

W Siede et al. Mutagenesis. 1986 Nov.

Abstract

Our studies on the REV2-dependent processes of DNA repair and u.v. mutagenesis in yeast are summarized and compared with the general features of DNA damage-induced mutagenesis in yeast. On the basis of the data available, we propose that mismatch repair is an essential process in u.v. mutagenesis. We assume that a photoproduct site in double-stranded DNA can be handled as a replicative mismatch leading to misinsertion opposite the lesion.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources