Comparison of high- and low-intensity exercise training early after acute myocardial infarction - PubMed (original) (raw)
Clinical Trial
Comparison of high- and low-intensity exercise training early after acute myocardial infarction
J A Blumenthal et al. Am J Cardiol. 1988.
Abstract
The effects of the intensity of exercise training on cardiorespiratory variables were investigated in a consecutive series of men with recent (median 8 weeks) acute myocardial infarction. Forty-five patients were randomly assigned either to a high- (65 to 75% maximum oxygen consumption rate [VO2max]) or to a low-intensity (less than 45% VO2max) exercise group. Patients engaged in medically supervised aerobic training 3 sessions a week for 12 weeks. With training, mean VO2max significantly increased by 11% (2.09 to 2.31 liters/min) within the high group and by 14% (1.93 to 2.21 liters/min) within the low group. Differences between groups were not statistically significant. Both groups also had comparable changes in heart rate, blood pressure and double-product at submaximal and maximal workloads. Analysis of blood lipids revealed that both groups experienced a significant increase in high density lipoprotein cholesterol. There were no significant changes in total serum cholesterol or triglycerides. These findings suggest that within an unselected population of patients after acute myocardial infarction referred for cardiac rehabilitation, low- and high-intensity exercise training produces relatively similar changes in cardiorespiratory variables during the initial 3 months of exercise training.
Similar articles
- Exercise training frequency in early post-infarction cardiac rehabilitation. Influence on aerobic conditioning.
Dressendorfer RH, Franklin BA, Cameron JL, Trahan KJ, Gordon S, Timmis GC. Dressendorfer RH, et al. J Cardiopulm Rehabil. 1995 Jul-Aug;15(4):269-76. doi: 10.1097/00008483-199507000-00003. J Cardiopulm Rehabil. 1995. PMID: 8542532 Clinical Trial. - Changes in Oxygen Consumption and Heart Rate After Acute Myocardial Infarction During 6-Month Follow-up.
Choe Y, Han JY, Choi IS, Park HK. Choe Y, et al. PM R. 2018 Jun;10(6):587-593. doi: 10.1016/j.pmrj.2017.11.015. Epub 2017 Dec 6. PM R. 2018. PMID: 29222074 - Does appropriate endurance exercise training improve cardiac function in patients with prior myocardial infarction?
Adachi H, Koike A, Obayashi T, Umezawa S, Aonuma K, Inada M, Korenaga M, Niwa A, Marumo F, Hiroe M. Adachi H, et al. Eur Heart J. 1996 Oct;17(10):1511-21. doi: 10.1093/oxfordjournals.eurheartj.a014715. Eur Heart J. 1996. PMID: 8909908 Clinical Trial. - Exercise training after acute myocardial infarction.
Dehn MM, Pansegrau DG, Mitchell JH. Dehn MM, et al. Cardiovasc Clin. 1978;9(3):117-32. Cardiovasc Clin. 1978. PMID: 361233 Review. No abstract available.
Cited by
- Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.
Blumenthal JA, Hinderliter AL, Smith PJ, Mabe S, Watkins LL, Craighead L, Ingle K, Tyson C, Lin PH, Kraus WE, Liao L, Sherwood A. Blumenthal JA, et al. Circulation. 2021 Oct 12;144(15):1212-1226. doi: 10.1161/CIRCULATIONAHA.121.055329. Epub 2021 Sep 27. Circulation. 2021. PMID: 34565172 Free PMC article. Clinical Trial. - Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.
Smith PJ, Mabe SM, Sherwood A, Doraiswamy PM, Welsh-Bohmer KA, Burke JR, Kraus WE, Lin PH, Browndyke JN, Babyak MA, Hinderliter AL, Blumenthal JA. Smith PJ, et al. J Alzheimers Dis. 2020;77(4):1793-1803. doi: 10.3233/JAD-200374. J Alzheimers Dis. 2020. PMID: 32925039 Free PMC article. Clinical Trial. - Trends in cardiorespiratory fitness: The evolution of exercise treadmill testing at a single Academic Medical Center from 1970 to 2012.
Kelly JP, Andonian BJ, Patel MJ, Huang Z, Shaw LK, McGarrah RW, Borges-Neto S, Velazquez EJ, Kraus WE. Kelly JP, et al. Am Heart J. 2019 Apr;210:88-97. doi: 10.1016/j.ahj.2019.01.001. Epub 2019 Jan 16. Am Heart J. 2019. PMID: 30743212 Free PMC article. - Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.
Blumenthal JA, Smith PJ, Mabe S, Hinderliter A, Lin PH, Liao L, Welsh-Bohmer KA, Browndyke JN, Kraus WE, Doraiswamy PM, Burke JR, Sherwood A. Blumenthal JA, et al. Neurology. 2019 Jan 15;92(3):e212-e223. doi: 10.1212/WNL.0000000000006784. Epub 2018 Dec 19. Neurology. 2019. PMID: 30568005 Free PMC article. Clinical Trial. - Influence of Kidney Function on Blood Pressure Response to Lifestyle Modifications: Secondary Analysis From the Exercise and Nutritional Interventions for Cardiovascular Health (ENCORE) Trial.
Tyson CC, Smith PJ, Sherwood A, Mabe S, Hinderliter AL, Blumenthal JA. Tyson CC, et al. J Clin Hypertens (Greenwich). 2016 Dec;18(12):1260-1267. doi: 10.1111/jch.12853. Epub 2016 Jun 24. J Clin Hypertens (Greenwich). 2016. PMID: 27338954 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical