A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor - PubMed (original) (raw)
. 1988 Apr 5;263(10):4520-2.
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- PMID: 3350799
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A 15-kDa interferon-induced protein is derived by COOH-terminal processing of a 17-kDa precursor
E Knight Jr et al. J Biol Chem. 1988.
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Erratum in
- J Biol Chem 1988 Jul 15;263(20):10040
Abstract
An interferon-induced 15-kDa protein is synthesized from a precursor of higher molecular weight; the precursor contains 165 amino acids (17 kDa), whereas the stable product (15 kDa) contains 156 amino acids. The stable 15-kDa form is derived from the precursor 17-kDa form by the removal of eight amino acids from the COOH terminus and the methionine from the NH2 terminus. The existence of the precursor 17-kDa protein can be demonstrated after brief periods of in vivo labeling with [35S]methionine and by translation of mRNA in vitro.
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